Examples of using Ipsc in English and their translations into Russian
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IPSC/ILO/WHO.
However, the study failed to obtain live chimeric mice with the iPSC line.
Therefore, it became possible to obtain iPSC from adult and even elderly patients.
Half page color advertising in the Match Website and Banner in the IPSC Website.
A practical strategy for iPSC differentiation and target cell purification is needed.
More detailed results of the research are available on the website of the company«IPSC»www. ipsc. am.
A typical instance of iPSC therapeutic application was Hanna J and his colleagues' work.
Furthermore, their data demonstrated significantly improved cardiac function following iPSC transplantation.
Future challenges will focus on how diseased iPSC models can faithfully reflect disease phenotypes.
Option for changing preamble duration for better performance mostly required for IPSC networks.
However, the iPSC strategy was extended rapidly across species since the initial derivation of mouse iPSCs.
Thus, more effects are still needed to derive clinical-grade iPSC lines and overcome so many challenges.
It was developed according to requirements of the International Practical Shooting Confederation IPSC.
Actually, many methods used for iPSC cardiac differentiation are based on the previous studies in ESCs.
The scientific community is sparing no effort to push the advancements in iPSC basic research and its clinical use.
Since 2010 the IPSC conducted 4 studies per year assessing the activities of the government, life quality and community needs.
Therefore, investigators put great efforts on exploring safer vectors to make iPSC more therapeutically applicable.
These studies(both on mouse and human iPSC lines) coincidentally indicated that cardiomyogenic potentials of iPSCs could be line-specific.
Thus, the increased neovascularization noted in the infarcted db/db andC57BL/6 mice is associated with improved cardiac function following iPSC transplantation 60.
Just within six years,the experimental achievements in iPSC research have generated great expectations in both clinicians and patients.
In summary, the iPSC research has been progressing with an amazing speed from the first onset, encouraging achievements have been unceasingly emerging and all these are just the start.
One direct consequence in therapeutic use may be that one iPSC line is effective in myocardial regeneration and repair but another not.
Published iPSC studies only reproduce disease phenotypes and drugs that have already been reported using other approaches such as transgenetic animal models or primary cells.
Post-treatment there was a significant increase in VSM andECs in the infarcted hearts following iPSC transplantation compared with MI and sham groups in both db/db and C57BL/6 animals.
Following CM lineage induction from iPSC, there are various in vitro and vivo conditioning strategies along with various delivery methods that involve the injection or implantation of cells, gels, and tissues 40-45.
The reagent only or combined with other inducers may be promising in future application to facilitate cardiac differentiation of different iPSC lines, especially those could not be substituted, e.g., patient-specific iPSCs.
In addition, it has been confirmed too that iPSC treatment was effective for cardiovascular disease, spinal cord injury and many other diseases[64-67];
Therefore, the development of cell reprogramming or iPSC technology may open up a new perspective to the quickly progressing field of cell-based therapy.
To date, iPSC models have been used to model a large number of genetic arrhythmias including LQT syndromes, catecholaminergic polymorphic ventricular tachycardia(CPVT), arrhythmogenic right ventricular cardiomyopathy(ARVD), and Overlap Syndrome 14,16-24.