Examples of using Decrease plasma concentrations in English and their translations into Slovak
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Medicine
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Dexamethasone is expected to decrease plasma concentrations of etravirine.
When co-administered with CHCs, many combinations of HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors,including combinations with HCV inhibitors can increase or decrease plasma concentrations of estrogen or progestins.
Dexamethasone is expected to decrease plasma concentrations of etravirine.
Ritonavir may decrease plasma concentrations of voriconazole.(induction of CYP450 enzymes by ritonavir).
Rifampicin and rifapentine are expected to decrease plasma concentrations of etravirine.
Nevirapine may decrease plasma concentrations of methadone by increasing its hepatic metabolism.
Carbazamepine, phenobarbital and phenytoin are expected to decrease plasma concentrations of etravirine.
Dexamethasone may decrease plasma concentrations of darunavir.(CYP3A induction).
Carbazamepine, phenobarbital and phenytoin are expected to decrease plasma concentrations of etravirine.
INTELENCE is expected to decrease plasma concentrations of these antiarrhythmics.
Other inducers of CYP3A4 such as phenobarbital, phenytoin and carbamazepine, may also decrease plasma concentrations of tadalafil.
Etravirine is expected to decrease plasma concentrations of cyclosporine, sirolimus or tacrolimus.
Induction As a moderate inducer of CYP2C9 and a mild inducer of CYP3A4 and glucuronidation,aprepitant can decrease plasma concentrations of substrates eliminated by these routes.
As a mild inducer of CYP2C9, CYP3A4 and glucuronidation,aprepitant can decrease plasma concentrations of substrates eliminated by these routes within two weeks following initiation of treatment.
Medicinal products that are potent inducers of P-gp or potent inducers of CYP2B6, CYP2C8, or CYP3A4(e.g. rifampicin, rifabutin, St. John's wort, carbamazepine, phenobarbital and phenytoin)may decrease plasma concentrations of sofosbuvir or velpatasvir leading to reduced therapeutic effect of sofosbuvir/velpatasvir.
As a mild inducer of CYP2C9, CYP3A4 and glucuronidation,aprepitant can decrease plasma concentrations of substrates eliminated by these routes.
Co-administration with strong CYP3Ainducers should be avoided since they may decrease plasma concentrations of cabazitaxel(see sections 4.2 and 4.5).
CYP2B6 induction has not been investigated in vivo andbrivaracetam may decrease plasma concentrations of medicinal products metabolised by CYP2B6(e.g. efavirenz).
Induction As a moderate inducer of CYP2C9 and a mild inducer of CYP3A4 and glucuronidation,aprepitant can decrease plasma concentrations of substrates eliminated by these routes within two weeks following initiation of dosing regimen.
A 3-hour hemodialysis session decreases plasma concentrations by approximately 50%.
St John's Wort decreased plasma concentrations of midazolam by about 20-40% associated with a decrease in terminal half-life of about 15-17%.
Carbamazepine decreases plasma concentrations of elvitegravir and cobicistat, which may result in loss of therapeutic effect and development of resistance.
Rifampicin substantially decreases plasma concentrations of atazanavir, which may result in loss of therapeutic effect of EVOTAZ and development of resistance to atazanavir.
Concomitant administration of dexamethasone with substances that are metabolised via CYP3A4 ortransported by P-gp could lead to increased clearance and decreased plasma concentrations of these substances.
Co-administration of Tybost with medicinal products that induce CYP3A iscontraindicated or is not recommended(see sections 4.3 and 4.5) because decreased plasma concentrations of cobicistat could result in plasma levels that are insufficient to achieve adequate pharmacoenhancement of atazanavir or darunavir.
Co-administration of EVOTAZ and medicinal products that induce CYP3A4 is contraindicated or not recommended(see sections 4.3 and 4.5) because, in addition to decreased plasma concentrations of atazanavir due to induction of CYP3A4, decreased plasma concentrations of cobicistat could result in cobicistat plasma levels that are insufficient to achieve adequate pharmacoenhancement of atazanavir.