Приклади вживання Adjuvant chemotherapy Англійська мовою та їх переклад на Українською
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The toxicity resulting from adjuvant chemotherapy was believed to be manageable.[19].
Dose-dense chemotherapy(DDC) has recently emerged as an effective method of adjuvant chemotherapy administration.
Adjuvant chemotherapy has been used in malignant melanoma, but there is little hard evidence to use chemotherapy in the adjuvant setting.
For seminoma, the three standard options are: active surveillance,adjuvant radiotherapy, or adjuvant chemotherapy.
For non-seminoma, the options include: active surveillance, adjuvant chemotherapy and retroperitoneal lymph node dissection.[30].
Adjuvant chemotherapy is effective in preventing the outgrowth of micrometastatic disease from colorectal cancer that has been removed surgically.
Research is beingcarried out to find out if giving chemotherapy after surgery(adjuvant chemotherapy) can help to reduce the risk of cancer coming back.
In the postoperative period, when the likelihood of recurrence or metastasis is large,there are additional courses of chemotherapy( adjuvant chemotherapy).
A regimen of neoadjuvant or adjuvant chemotherapy will be counted as first-line chemotherapy if the patient progressed within 12 months of the last dose.
For advanced cervical cancers, further research is needed to determine the efficacy,toxicity and effect on the quality of life of adjuvant chemotherapy.[27].
For example, because side effects of adjuvant chemotherapy can range from nausea to loss of fertility, physicians regularly practice caution when prescribing chemotherapy.[7].
Vaccinogen plans to conduct a pilot program inparallel with ACTIVE to evaluate OncoVAX in combination with an adjuvant chemotherapy treatment for stage III colon cancer patients.
Studies have shown that fluorouracil is an effective adjuvant chemotherapy among patients with microsatellite stability or low-frequency microsatellite instability, but not in patients with high-frequency microsatellite instability.[15][16].
In completely resected medulloblastoma,5-year survival rate is 85% if adjuvant chemotherapy and/or craniospinal irradiation is performed, and just 10% if no adjuvant chemotherapy or craniospinal irradiation is used.
It has beenknown for at least 30 years that adjuvant chemotherapy increases the relapse-free survival rate for patients with breast cancer[22] In 2001 after a national consensus conference, a US National Institute of Health panel concluded:“Because adjuvant polychemotherapy improves survival, it should be recommended to the majority of women with localized breast cancer regardless of lymph node, menopausal, or hormone receptor status.”[2].
In early stageone small cell lung carcinoma, adjuvant chemotherapy with gemzar, cisplatin, paclitaxel, docetaxel, and other chemotherapeutic agents, and adjuvant radiotherapy is administered to either the lung, to prevent a local recurrence, or the brain to prevent metastases.
Adjuvant(postoperative) chemotherapy is prescribed to most patients after mastectomy.
In testicular cancer, adjuvant either radiotherapy or chemotherapy may be used following orchidectomy.
The results showed that curative and adjuvant cytotoxic chemotherapy only showed a 2.3% success in 5-year survival in Australian adults, and 2.1% in Americans.
This study further corroborated that the"presence of antimetastatic immune protection in MSI-H CRCpatients may explain recent findings that adjuvant 5-FU chemotherapy has no beneficial or even adverse effects in this collective.".
In breast cancer, adjuvant therapy may consist of chemotherapy(doxorubicin, herceptin, paclitaxel, docetaxel, cyclophosphamide, fluorouracil, and methotrexate) and radiotherapy, especially after lumpectomy, and hormonal therapy(tamoxifen, femara).
The optimal scheme of adjuvant therapy(radiotherapy, radiosurgery, chemotherapy) is selected on the basis of pathohistological and immunohistochemical tumor studies.
Hyperthermia therapy or heat therapy is also a kind of adjuvant therapy that is given along with radiation or chemotherapy to boost the effects of these conventional treatments.
Although now already established drugs for cancer chemotherapy brain to overcome barriers, though chemotherapy is an auxiliary,or as they say oncologists adjuvant treatment for brain cancer in this case.
Systemic therapy consists of chemotherapy, immunotherapy or biological response modifiers or hormone therapy.[6] Oncologists use statistical evidence to assess the risk of disease relapse before deciding on the specific adjuvant therapy.
Despite the initial pushback from the breast cancer surgeons who believed that their radical mastectomies were sufficient in removing all traces of cancer, the success of Bonadonna's and Fisher's trials brought adjuvant therapy to the mainstream in oncology.[1] Since then, the field of adjuvant therapy has greatly expanded to include awide range of adjuvant therapies to include chemotherapy, immunotherapy, hormone therapy, and radiation.
In advanced-stage endometrial cancer, adjuvant therapy is typically radiation, chemotherapy, or a combination of the two.
In early stage cervical cancers, research suggests that adjuvant platinum-based chemotherapy after chemo-radiation may improve survival.
In 2015, a comprehensive meta-analysis of 47 trials and11,107 patients revealed that NSCLC patients benefit from adjuvant therapy in the form of chemotherapy and/or radiotherapy.