Примери за използване на Biliary excretion на Английски и техните преводи на Български
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Improved biliary excretion;
Orlistat, M1 andM3 are all subject to biliary excretion.
Biliary excretion may also contribute to the elimination.
Eribulin is eliminated primarily by biliary excretion.
Biliary excretion is insignificant(less than 5% of a dose).
Spiramycin is eliminated primarily by biliary excretion.
Biliary excretion appears to be another important elimination pathway.
Elimination of simeprevir occurs via biliary excretion.
Biliary excretion of parent drug was the major route of elimination for voxilaprevir.
Eribulin is mainly(up to 70%) eliminated through biliary excretion.
Faced the problem of biliary excretion, it is recommended to eat bran with milk thistle.
Erlotinib is eliminated by hepatic metabolism and biliary excretion.
Data in rats showed some biliary excretion(about 30%), primarily as metabolites.
Glucuronidation is the main metabolic pathway for deferasirox, with subsequent biliary excretion.
The major elimination pathways of letermovir is biliary excretion as well as direct glucuronidation.
Combined excretion of verteporfin and BPD-DA in human urine was less than 1%,suggesting biliary excretion.
These data indicate that biliary excretion of parent drug was a major route of elimination for velpatasvir.
The elimination pathways of letermovir in vivo are biliary excretion and glucuronidation.
Bosentan is eliminated by biliary excretion following metabolism in the liver by the cytochrome P450 isoenzymes, CYP2C9 and CYP3A4.
Rimonabant is mainly eliminated by metabolism and subsequent biliary excretion of metabolites.
As metabolism appears to be limited, biliary excretion of unchanged pixantrone may be the major elimination pathway.
Enterohepatic recirculation may be an explanation as extensive biliary excretion was seen in the rat.
Biliary excretion of the metabolites increases in the event of kidney failure, proportionally to the severity of the change in renal function.
Overall, the primary route of elimination for tigecycline is biliary excretion of unchanged tigecycline.
Preclinical studies indicate that aliskiren andketoconazole co-administration enhances aliskiren gastrointestinal absorption and decreases biliary excretion.
Pasireotide is eliminated mainly via hepatic clearance(biliary excretion), with a small contribution of the renal route.
OATP isoforms, MRP2 and breast cancer resistance protein(BCRP)are transporters associated with the glucuronides' biliary excretion.
After intravenous dosing in patients, no significant biliary excretion of glimepiride or its M1 metabolite was observed.
Biliary excretion of unchanged medicinal product may contribute to the elimination of doravirine, but this elimination route is not expected to be significant.
Hepatic uptake of pixantrone is possibly mediated by OCT1 active transporters and biliary excretion by P-gp and BCRP.