Примери за използване на Chromosome aberration на Английски и техните преводи на Български
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In vitro Chromosome aberration(473).
In vivo Micronucleus assay/Mammalian bone marrow chromosome aberration test.
Key words: cytogenetics, chromosome aberrations, chromosomal instability.
Genetic changes can be divided in gene mutations and chromosome aberrations.
It can lead to chromosome aberrations in your future baby and can thwart the male hormone system.
Mutagenicity(should at least include a gene mutation test and a chromosome aberration test);
Key words: multiple myeloma, chromosome aberrations, genome profiling.
Although these investigations revealed partially contradictory results,particularly a potential to induce chromosome aberrations cannot be excluded.
Key words: cytogenetics, chromosome aberrations, chromosome instability, myeloid disorders.
Puregon showed no mutagenic potential in the Ames test andin the in vitro chromosome aberration test with human lymphocytes.
Pemetrexed was not mutagenic in either the in vitro chromosome aberration test in Chinese hamster ovary cells, or the Ames test. Pemetrexed has been shown to be clastogenic in the in vivo micronucleus test in the mouse.
Patiromer was not genotoxic in the reverse mutation test(Ames assay), chromosome aberration or rat micronucleus assays.
Apremilast did not induce mutations in an Ames assay or chromosome aberrations in cultured human peripheral blood lymphocytes in the presence or absence of metabolic activation.
With somatropins, in vitro and in vivo genotoxicity studies on gene mutations and induction of chromosome aberrations have been negative.
Paclitaxel has been shown to be clastogenic in vitro(chromosome aberrations in human lymphocytes) and in vivo(micronucleus test in mice).
In an in vitro mammalian cytogenetic test with metabolic activation,sevelamer hydrochloride caused a statistically significant increase in the number of structural chromosome aberrations.
Pemetrexed was not mutagenic in either the in vitro chromosome aberration test in Chinese hamster ovary cells, or the Ames test.
Amprenavir was not mutagenic or genotoxic in a battery of in vivo and in vitro genetic toxicity assays, including bacterial reverse mutation(Ames Test), mouse lymphoma,rat micronucleus, and chromosome aberration in human peripheral lymphocytes.
Docetaxel has been shown to be mutagenic in the in vitro micronucleus and chromosome aberration test in CHO-K1 cells and in the in vivo micronucleus test in the mouse.
Positive genotoxic effects were obtained for imatinib in an in vitro mammalian cell assay(Chinese hamster ovary) for clastogenicity(chromosome aberration) in the presence of metabolic activation.
Isavuconazole was negative in a bacterial reverse mutation assay,was weakly clastogenic at cytotoxic concentrations in the L5178Y tk+/- mouse lymphoma chromosome aberration assay, and showed no biologically relevant or statistically significant increase in the frequency of micronuclei in an in vivo rat micronucleus test.
Pazopanib did not cause genetic damage when tested in genotoxicity assays(Ames assay,human peripheral lymphocyte chromosome aberration assay and rat in vivo micronucleus).
Thiocolchicoside itself did not induce gene mutation in bacteria(Ames test),in vitro chromosomal damage(chromosome aberration test in human lymphocytes) and in vivo chromosomal damage(in vivo micronucleus in mouse bone marrow administered intraperitoneally).
Positive genotoxic effects were obtained for imatinib in an in vitro mammalian cell assay(Chinese hamster ovary) for clastogenicity(chromosome aberration) in the presence of metabolic activation.
Positive genotoxic effects were obtained for imatinib in an in vitro mammalian cell assay(Chinese hamster ovary)for clastogenicity(chromosome aberration) in the presence of metabolic activation at a concentration of 125 μg/ml. Two intermediates of the manufacturing process, which are also present in the final product.
BZA was not genotoxic or mutagenic in a battery of tests, including in vitro bacterial reverse mutation assay, in vitro mammalian cell forward mutation assay at the thymidine kinase(TK/-) locus in L5178Y mouse lymphoma cells,in vitro chromosome aberration assay in Chinese hamster ovary(CHO) cells, and in vivo mouse micronucleus assay.
Lapatinib was not clastogenic or mutagenic in a battery of assays including the Chinese hamster chromosome aberration assay, the Ames assay, human lymphocyte chromosome aberration assay and an in vivo rat bone marrow chromosome aberration assay.
Ombitasvir and its major inactive human metabolites(M29, M36) were not genotoxic in a battery of in vitro or in vivo assays,including bacterial mutagenicity, chromosome aberration using human peripheral blood lymphocytes and in vivo mouse micronucleus assays.
Sofosbuvir was not genotoxic in a battery of in vitro or in vivo assays,including bacterial mutagenicity, chromosome aberration using human peripheral blood lymphocytes and in vivo mouse micronucleus assays.
Dasabuvir was not genotoxic in a battery of in vitro or in vivo assays,including bacterial mutagenicity, chromosome aberration using human peripheral blood lymphocytes and in vivo rat micronucleus assays.