Примери за използване на Did not induce на Английски и техните преводи на Български
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Mirabegron did not induce CYP1A2 or CYP3A.
When tested in animal models,lornoxicam did not induce liver enzymes.
Piperaquine did not induce malformation in rats and rabbits.
Studies also concluded thatdaily doses of CBD(700mg) for 6 weeks did not induce any toxicity in patients.
Vinflunine did not induce peripheral neuropathy in animals.
In vitro studies in rat hepatocytes also showed that ambrisentan did not induce Pgp, BSEP or MRP2 protein expression.
Gilteritinib did not induce gene mutation or chromosomal aberrations in vitro.
In an in vitro study with human hepatocytes, lenalidomide,at various concentrations tested did not induce CYP1A2, CYP2B6, CYP2C9, CYP2C19 and CYP3A4/5.
Apixaban did not induce CYP1A2, CYP2B6, CYP3A4/5 at a concentration up to 20 µM.
In vitro studies indicated that carfilzomib did not induce human CYP3A4 in cultured human hepatocytes.
MMAE did not induce any major CYP450 enzymes in primary cultures of human hepatocytes.
In vitro, dolutegravir did not induce CYP1A2, CYP2B6 or CYP3A4.
BindRen did not induce any clinically relevant reduction in the absorption of vitamins A, D, E or K during clinical studies of up to one year.
In clinical studies, caspofungin did not induce the CYP3A4 metabolism of other substances.
Rotigotine did not induce gene mutations in the Ames test, but did show effects in the in vitro Mouse Lymphoma Assay with metabolic activation and weaker effects without metabolic activation.
When tested in vitro brivaracetam did not induce CYP1A1/2 but induced CYP3A4 and CYP2B6.
Ixazomib did not induce CYP1A2, CYP2B6, and CYP3A4/5 activity or corresponding immunoreactive protein levels.
In an embryo-foetal developmental toxicity study conducted in mice,the murine surrogate molecule crossed the placenta and did not induce embryotoxicity, or teratogenicity(see section 5.3).
Ziconotide did not induce bacterial gene mutation and was not genotoxic.
Repeated treatment with REKOVELLE of patients with pre-existing or treatment-induced anti-FSH antibodies did not increase the antibody titre,was not associated with decreased ovarian response, and did not induce immune-related adverse events.
Cabazitaxel did not induce mutations in the bacterial reverse mutation(Ames) test.
In an embryo-foetal developmental toxicity study performed in mice, the murine surrogate crossed the placenta to a limited extent(foetal-to-maternal serum concentration ratio<1%) and did not induce embryo-foetal toxicity or teratogenicity.
Rilpivirine did not induce chromosomal damage in the in vivo micronucleus test in mice.
In a study designed to assess discontinuation symptoms by the Discontinuation Emergent Signs and Symptoms(DESS) check-list in patients with remitted depression,Thymanax did not induce discontinuation syndrome after abrupt treatment cessation.
Fertility Insulin lispro did not induce fertility impairment in animal studies(see section 5.3).
In a trial designed to assess discontinuation symptoms by the Discontinuation Emergent Signs and Symptoms(DESS) check-list in patients with remitted depression,agomelatine did not induce discontinuation syndrome after abrupt treatment cessation.
However, it did not induce mutagenicity in the Ames test or the CHO/HGPRT gene mutation assay.
The fosaprepitant 150 mg single dose did not induce CYP3A4 on Days 1 and 4 in the midazolam interaction study.
Sunitinib did not induce structural chromosome aberrations in human peripheral blood lymphocyte cells in vitro.
In clinical studies, caspofungin did not induce or inhibit the CYP3A4 metabolism of other medicinal products.