Примери за използване на Maximum observed на Английски и техните преводи на Български
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Amax= maximum observed% activity;
In vitro studies show that decitabine does not inhibit norinduce CYP 450 enzymes up to more than 20-fold of the therapeutic maximum observed plasma concentration(Cmax).
Slight maximum observed in the autumn and winter.
Co-administration of tolvaptan and ketoconazole resulted in a 440% increase in area under time-concentration curve(AUC) and248% increase in maximum observed plasma concentration(Cmax) for tolvaptan.
Tmax= time of maximum observed% activity, N/A= not available.
The effect of the interactions on the plasma concentration is summarised in table 1(increase is indicated as“↑” and decrease as“↓”,area under the plasma concentration versus time curve as“AUC”, maximum observed concentration as Cmax).
The time to maximum observed concentration(tmax) is expected at the end of infusion(EOI) or soon after EOI.
Volume of distribution(Vd) was consistent with plasma volume,and the mean maximum observed plasma concentration(Cmax) and terminal half-life(t1/2) values increased with dose.
The maximum observed plasma concentrations for prilocaine and ortho-toluidine were 0.08 µg/mL and 0.01 µg/mL respectively.
The residential price index is now less than 1% below the maximum observed in 2010,' said Ricardo Guimarães, director of Confidencial Imobiliário.
However, the maximum observed plasma concentrations as well as volumes of distribution estimates were similar across the groups.
Interactions between dolutegravir, abacavir, lamivudine and co-administered medical products are listed in Table 1(increase is indicated as“↑”, decrease as“↓”, no change as“↔”,area under the concentration versus time curve as“AUC”, maximum observed concentration as“Cmax”).
The maximum observed plasma concentration for lidocaine, monoglycinexylidide and 2,6-xylidine were 0.41, 0.03 and 0.01 µg/mL respectively.
In vitro telotristat(active metabolite) caused a concentration dependent increase in CYP2B6 mRNA levels(> 2-fold increase and>20% of the positive control, with a maximum observed effect similar to the positive control), suggesting possible CYP2B6 induction(see section 4.5).
Maximum observed plasma concentrations were reached within 0.5 to 2 hours(median 1 hour) in the fasted state and absolute bioavailability was about 0.6%.
Interactions between dolutegravir and co-administered medicinal products are listed in Table 2(increase is indicated as“↑”, decrease as“↓”, no change as“↔”,area under the concentration versus time curve as“AUC”, maximum observed concentration as“Cmax”, concentration at end of dosing interval as“Cτ”).
Maximum observed plasma concentrations were reached within 0.5 to 2 hours(median 1 hour) in the fasted state and absolute bioavailability was about 0.6%.
Following repeated daily dosing of 1 mg talazoparib to patients, the geometric mean(% coefficient of variation[CV%])area under the plasma concentration-time curve(AUC) and maximum observed plasma concentration(Cmax) of talazoparib at steady-state was in the range of 126(107) ng•hr/mL to 208(37) ng•hr/mL and 11(90) ng/mL to 19(27) ng/mL, respectively.
In subsequent doses, mean maximum observed plasma concentrations ranged from 67 to 106 ng/ml for the 1.0 mg/m2 dose and 89 to 120 ng/ml for the 1.3 mg/m2 dose.
Steady state digoxin concentrations have been increased(1.3-fold increase in maximum observed plasma concentration[Cmax] and 1.2-fold increase in area under the plasma concentration-time curve over the dosing interval AUC) when co administered with multiple once daily 60 mg doses of tolvaptan.
In subsequent doses, mean maximum observed plasma concentrations ranged from 67 to 106 ng/ ml for the 1.0 mg/ m2 dose and 89 to 120 ng/ ml for the 1.3 mg/ m2 dose.
Abbreviations: Cmax: maximum observed activity; AUC: area under the curve; MRT: mean residence time; CL: clearance; Vss: body weight adjusted volume of distribution at steady-state.
Abbreviations: Cmax= maximum observed plasma concentration; CV= coefficient of variation; AUCinf= area under the plasma concentration-time profile from time zero extrapolated to infinite time; t½= terminal half-life; CL= clearance; Vss= steady-state volume of distribution.
Steady state digoxin concentrations were increased(1.3-fold in maximum observed plasma concentration[Cmax] and 1.2fold in area under the plasma concentration-time curve over the dosing interval AUC) when coadministered with multiple once daily 60 mg doses of tolvaptan.
N/A 4.2 0.75 178 1583 1686 Amax= maximum observed% activity; AUC0-t= area under the concentration-time curve from time 0 to the last measurable concentration; AUC0-∞= area under the concentration-time curve from time 0 extrapolated to infinity; t½= terminal half-life; Tmax= time of maximum observed% activity, N/A= not available.
The maximum effect is observed for 8-10 weeks.
After entering the body means the maximum concentration observed after two or three hours.
Maximum popularity rightly observed in tiles for bathrooms.
The maximum effect is observed in 1 hour.
The maximum effect is observed after a course of 15-20 sessions.