Eksempler på bruk av Response and tolerability på Engelsk og deres oversettelse til Norsk
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Dose escalation should be based upon clinical response and tolerability.
Additionally, patient response and tolerability should be carefully monitored and dose should be adapted accordingly.
Dose increase or reduction is recommended based on patient response and tolerability.
Based on individual patient response and tolerability, the dose may be increased to 300 mg(15 ml) per day after 1 week.
The dose may be increased to 6 mg once daily based on clinical response and tolerability.
Depending on the clinical response and tolerability in the individual patient, the dose can be increased to 10 mg twice daily.
The dose can be increased to 10 mg twice daily based on individual clinical response and tolerability.
The dose may be lowered to 2 mg daily based on individual response and tolerability; however, limited efficacy data are available for Detrol 2 mg.
Dose increases in patients with mild and moderate hepatic impairment should be based on clinical response and tolerability.
If concomitant use is warranted,patient response and tolerability should be monitored and dose adjustments made if required(see section 4.2).
Thereafter, the total daily dose is increased by a maximum of 150 mg every week,according to the individual patient response and tolerability.
If concomitant use is warranted,patient response and tolerability should be monitored and dose should be adapted accordingly(see section 4.4).
In populations where the dose may be increased to 8 mg once daily,the dose increase should be preceded by an evaluation of the individual response and tolerability.
Dosing intervals should be modified according to clinical response and tolerability(see sections 4.4 and 5.2).
According to clinical response and tolerability, after a minimum of 2 days the dose may be increased by 200 mg/day, to the maximum recommended dose of 600 mg/day 15 ml/day.
The combination of trazodone with indinavir/ritonavir should be used with caution, initiating trazodone at the lowest dose and monitoring for clinical response and tolerability.
Caution should be exercised and careful assessment of therapeutic response and tolerability should be made before increasing to daily dosing after one week.
Depending on response and tolerability, Vimpat 150 mg tablets may be taken twice a day during the third weekand Vimpat 200 mg tablets twice a day during the fourth week.
The total daily starting dose is 150 mg/day and during the titration period the total daily dose should be increased by a maximum of 150 mg every week,according to the individual patient response and tolerability.
According to clinical response and tolerability, the dose may be increased by 400 mg/day increments, as frequently as every two days, up to a maximum recommended dose as indicated in the table below.
Vimpat treatment initiation pack contains 4 different packages(one for each tablet strength) with 14 tablets each,for the first 2 to 4 weeks of therapy depending on the patient's response and tolerability.
Depending on response and tolerability, the maintenance dose can be further increased by 50 mg twice a day every week, to a maximum recommended daily dose of 400 mg 200 mg twice a day.
If an adequate reduction in alkaline phosphatase and/or total bilirubin has not been achieved after 3 months of OCALIVA 5 mg once weekly, and the patient is tolerating the medicinal product, increase the dose of OCALIVA to 5 mg twice weekly(at least three days apart between doses) and subsequently to 10 mg twice weekly(at least three days apart between doses)depending on response and tolerability.
Depending on response and tolerability, the maintenance dose can be further increased at weekly intervals by 50 mg twice a day(100 mg/day), up to a maximum recommended daily dose of 400 mg(200 mg twice a day).
Depending on response and tolerability, the maintenance dose can be further increased at weekly intervals by 50 mg twice a day(100 mg/day), up to a maximum recommended maintenance daily dose of 300 mg twice a day(600 mg/day).
Based on individual patient response and tolerability, the dose may be increased to 300 mg(15 ml) per day after an interval of 3 to 7 days, and if needed, to a maximum dose of 600 mg(30 ml) per day after an additional 7-day interval.
Patients should be closely monitored for tolerability and clinical response when adding or removing cytochrome P450 inducers or inhibitors, since perampanel plasma levels can be decreased or increased; the dose of perampanel may need to be adjusted accordingly.