Exemplos de uso de Complement levels em Inglês e suas traduções para o Português
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Complement levels were in the inferior normal range.
At that time, rheumatoid factor and anti-nuclear factor ANF were negative and complement levels were normal.
Low complement levels were seen in 8% of patients.
Proteinuria and other findings may or may not be present, and serum complement levels are typically normal.
In addition, serum complement levels are usually low, reflecting the disease activity.
In cutaneous leishmaniasis, significant changes in the frequency of autoantibodies or complement levels were not observed.
Inflammatory markers associated with the disease may be elevated in cases of myocarditis,along with reduction in serum complement levels.
Her complement levels were normal, ANA was positive 1/200 and all other autoantibodies including antiliver antibodies and cryoglobulins were persistently negative.
In the present study, we could not demonstrate any correlation between serum MBL levels and Complement levels, SLE disease activity or cumulative damage.
Decreased complement levels was also evident only in patients with visceral disease 13.3% of patients had significantly decreased levels of C3.
Further laboratory analysis revealed that ten 26% JSLE children had hypergammaglobulinemia and 12 31% had low complement levels compared to none in the control group p< 0.05.
In patients with low complement levels, normalization of C3 and C4 was observed by Week 52 in 38% and 44% of patients receiving Benlysta and in 17% and 19% of patients receiving placebo.
Before testing, the sera were identified, thawed, and divided in aliquots for posterior determination of antinuclear antibodies, rheumatoid factor RF,antiphospholipid antibodies, and complement levels.
Cases with low serum complement levels, no proteinuria, systemic disease, chronic viral infection, any suspect of immune-mediated disease, congenital nephrotic syndrome, or familial history of renal disease suggesting a hereditary glomerulopathy were excluded.
In those two patients with clinical activity of the disease,there was a trend to present normal or lower than normal complement levels during the severe disease's activity period.
Roxo Jr et al. measured complement levels in 10 Brazilian children during and after meningococcal meningitis to evaluate the functional activity of the classical and alternative pathways of the complement system, as well as the levels of C3, C4, and factor B during the first episode of the meningococcal infection, and during the convalescence period.
Moreover, when an immunodeficiency disease is suspected, initial laboratory screening should include a complete blood count with differential andmeasurement of serum immunoglobulin and complement levels.
In addition, the treatment with MMF resulted in significant reduction of hypergammaglobulinemia andrheumatoid factors as well as an increase of complement levels and leukocytes/neutrophils count, suggesting that MMF also might be effective in treating pSS-associated leukopenia.
The proposal was finalized with a total of 1676 occurrences of DeCS descriptors: 1189 occurrences 71% resulting from descriptors collected during the search and487 occurrences 29% resulting from descriptors added to complement levels.
Thus, in addition to anti-LPL association with hypertriglyceridemia already described, our previous results demonstrated a strong association with disease's activity, measured by SLEDAI score,by reduced complement levels, either by total hemolytic activity or by fractions in the same system C3 and C4, as well as high sensitive CRP levels. .
Although SLEDAI correlated only with anti-dsDNA antibodies, there was association between several of the tested autoantibodies to chromatin components and parameters indicative of disease activity,such as proteinuria and low complement levels.
The diagnosis of AGN was based on the history of a previous 7 to 21 days purulent upper airway or skin infection, and clinical and laboratory parameters, such as complete blood count and blood biochemistry electrolytes, urea, creatinine, lipid profile, serum protein profile,serum complement levels C3 and C4, serum anti-streptolysin O, urinalysis, and 24-hour proteinuria.
Complementary laboratorial exams revealed normal inflammatory tests, negative antineutrophil cytoplasmic antibodies ANCA, fine speckled and dense anti-nuclear factor ANF at 1/160,presence of anti-Ro SSA autoantibodies by ELISA, and normal complement levels.
Laboratory tests corroborate the hypothesis of active SLE showing leucopenia 3800 leukocytes/mm, lymphopenia 798 lymphocytes/mm, homogeneous antinuclear antibodies ANA> 1:320, positive anti-DNA, reactive C-protein 92 mg/L,erythrocyte sedimentation rate of 67 mm and complement levels C3 and C4 undetectable.
Univariate and multivariate analysis of the primary endpoint in pre-specified subgroups demonstrated that the greatest benefit was observed in patients with higher disease activity including patients with SELENA SLEDAI scores≥ 10,patients requiring steroids to control their disease, and patients with low complement levels.
Several literature reports have suggested that the administration of rituximab monoclonal anti CD20antibody is an alternative treatment in certain refractory cases of gemcitabine-associated TMA;it can produce favorable responses because this illness is associated with immune complexes as is suggested in our case by the decrease of serum complement levels.
There was no correlation between MBL deficiency and serum Complement component levels, regardless of the severity of MBL deficiency Table 2.