Examples of using Epitopes in English and their translations into German
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Colloquial
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Official
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Ecclesiastic
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Medicine
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Financial
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Ecclesiastic
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Political
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Computer
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Programming
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Official/political
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Political
There are two types of epitopes: continuous and discontinuous.
Antigens with 1 epitope antigens with 2 epitopes.
Discontinuous epitopes are regions that are present only in the folded conformation of a protein.
A universal HIER technique suitable for all epitopes does not exist.
Restricted epitopes(n=1720) from selected disease groups, obtained from the Immune Epitope Database.
Depending on its size and structure, an antigen may contain many different epitopes.
Continuous epitopes are a liner sequence of amino acids that are recognized by the antibody.
By contrast, polyclonal antibodies can bind to multiple epitopes on an antigen;
Monoclonal antibodies(mab) are available here the epitopes are well described as well as the reactivity of each antibody in different techniques.
Two antibodies in the kit specifically bind with different epitopes of the antigens.
Since polyclonal antibodies recognize different epitopes and with different affinities, it is difficult to identify the map the location of epitope using polyclonal antibodies.
These assays measured antibodies against neutralizing epitopes for each HPV type.
In many cases, these are linear antigens with repetitve epitopes which are able to crosslink multiple B cell receptors or additional pattern recognition receptors.
These antibodies are synthesised by B lymphocytes as a reaction to epitopes present in infectious agents.
Spatially separated from the E2-ubiquitin binding site, RING ligases possess various substrate-bindingdomains which recognise specific substrate protein epitopes.
This showed that the inactivation process preserved the epitopes rather than destroyed them.
For the production of our CE-marked products we use high-grade raw material,for example synthetic and recombinant epitopes.
Since an antigen can have multiple different epitopes, a number of antibodies can bind to the protein.
Immunohistology(= immunohistochemistry, IHC) is used in paraffin embedded,formalin fixated tissues to search for certain epitopes antigens.
These antibodies recognize and bind to many different epitopes of a single antigen and hence can form lattices with the antigens.
The ELISAs for human a-synuclein allow detection of total a-synuclein(MONO), pathological a-sheet rich oligomers(PATHO)or multiple epitopes on aggregates MULTI.
Antigens are known tocontain specific antigenic determinants(which are epitopes), while antibodies contain antigen-binding sites which are paratopes.
In most cases, a biological macromolecule contains several independent structures ableto elicit an antibody response, so-called antigenic determinants or epitopes.
HIER using an appropriate pHsolution improves the staining of some antibodies by exposing epitopes within tissue that have been masked during fixation.
There she showed that insulin mimetopes she optimized were significantly more efficient in inducing a tolerance through regulatoryT cells towards insulin than their natural counterparts epitopes.
Tris-EDTA-based solutions break protein cross-links and can therefore unmask antigens and epitopes in formalin-fixed and paraffin-embedded tissue sections.
Previous studies had shown that insulin mimetopes were significantly more efficient in inducing a tolerance through regulatoryT cells towards insulin than their natural counterparts epitopes.
BiondVax's M-001 vaccine candidate,consisting of nine widely conserved flu epitopes, is designed to protect against current and future, seasonal and pandemic flu strains.
The identification of heteromer and homomer molecules by antibody-dependent assays is predominantlyutilized with GPCRs that are uniquely tagged with epitopes and they are efficient in lysed or fixed cells.
Furthermore, these technologies are suitable for the development of adjuvant free vaccines as well as for the ex vivo expansion of t cells,the identification of new t cell epitopes and to test novel drugs and immune therapies concerning their functionality and possible side effects.