Examples of using Postsynaptic in English and their translations into Russian
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Colloquial
AMPA generates fast excitatory postsynaptic potentials EPSP.
Its mechanism of action is biphasic- at low doses it blocks presynaptic dopamine receptors andat higher doses it blocks postsynaptic receptors.
This is at the level of postsynaptic depolarization patterns.
Spike timing-dependent plasticity(STDP) refers to the timing of presynaptic and postsynaptic action potentials.
The metabotropic action of postsynaptic KAR also induces NMDA-independent long-term potentiation.
It is a competitive antagonist of acetylcholine on postsynaptic muscarine receptors.
However, rise anddecay times for postsynaptic potentials generated by KARs are slower than for AMPA postsynaptic potentials.
PP А B indicates percentage of evoked responses transmitted from presynaptic to postsynaptic subnetwork.
This endocannabinoid-mediated system permits the postsynaptic cell to control its own incoming synaptic traffic.
To induce synaptic plasticity, high frequency tetanic stimulation by two groups of electrodes located in the area of pre- and postsynaptic neurons was applied.
Effect of distribution of glycine receptors on the postsynaptic membrane of neurons on the concentration gradient of chloride ions.
Tetanic stimulation was applied using two sets of electrodes:4"presynaptic" electrodes in chamber A and 4"postsynaptic" electrodes in chamber B Figure 3.
The venom consists of both pre-synaptic and postsynaptic neurotoxins(dendrotoxins), cardiotoxins, calcicludine, and fasciculins.
This parameter indicates the efficiency of bioelectrical signal transmission between pre- and postsynaptic subpopulations of neural cells.
When multiple EPSPs occur on a single patch of postsynaptic membrane, their combined effect is the sum of the individual EPSPs.
There is also a KAR-mediated NMDAR-independent long-term suppression,which can be caused by prolonged low-frequency stimulation or postsynaptic depolarization 66.
The kainate receptors have a wide functional spectrum of postsynaptic generation of exciting internal currents in the hippocampus 86.
The excitatory postsynaptic potential(EPSP) produced by activation of an N-Methyl-D-Aspartic acid(NMDA) receptor also increases the concentration of Ca2+ in the cell.
The released glutamate binds to glutamate receptors on the postsynaptic membrane, initiating the release of Mg 2+ and blocking NMDA receptors.
In vertebrates, GABA acts at inhibitory synapses in the brain by binding to specific transmembrane receptors in the plasma membrane of both pre- and postsynaptic neuronal processes.
As a result, it has been touted as a preferential postsynaptic 5-HT1A receptor agonist and has been investigated as a novel potential antidepressant.
The 5-HT1A receptors in the raphe nucleus are largely somatodendritic autoreceptors,whereas those in other areas such as the hippocampus are postsynaptic receptors.
Cotransmission allows for more complex effects at postsynaptic receptors, and thus allows for more complex communication to occur between neurons.
Most of the studies on the synapses of mossy fibers in the hippocampal CA3 area in vertebrates address the presynaptic kainate receptors; however, the postsynaptic functions of these receptors are less studied.
The kainate receptors act on both presynaptic and postsynaptic neuron endings, controlling the excitatory and inhibitory synaptic transmission and the glia function.
Connections in which signals propagate in one direction are the most interesting because pre- and postsynaptic cells involved in them are in separate chambers.
The spatial distribution of the receptors on the postsynaptic membrane, along with their number, determines the amplitude of local variation of the ion concentration in the neuron.
It has been shown that a short-term high-frequency stimulation of mossy fibers causes slow EPSC mediated by postsynaptic high affinity kainate receptors in CA3 neurons 87, 88.
It is also known that the metabotropic effect of postsynaptic KAR increases the excitability of neurons by inhibiting hyperpolarization caused by potassium current in pyramidal cells of the CA1 region of the hippocampus 85.
A number of scientists started to investigate the possibility of beta oligomers to affect synaptic functions by changing such synaptic proteins as postsynaptic density proteins 95(PSD95)[22] and glutamate receptors 23.