Examples of using Cmax values in English and their translations into Slovak
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AUC or Cmax values.
Cmax values were dose proportional.
The corresponding plasma Cmax values were 24 ng/ml and 47 ng/ml.
Cmax values obtained at the end of infusion were higher for BPD-MAD than for BPD-MAC.
The corresponding plasma Cmax values were 24 ng/ml and 47 ng/ml, respectively.
The Phase 1 pharmacokinetics showed proportionality within the dose interval(0.5- 8 mg)as reflected in Cmax values.
For rosiglitazone, Cmax values were decreased by approximately 32% with food.
In younger p atients aged 2-5 years absorption,based on Cmax values, was higher compared to adults.
AUC and Cmax values in children in this study were consistent with those observed in adults.
In addition, N-desmethyl metabolite AUC and Cmax values were significantly increased 79% and 200% respectively.
Higher Cmax values than in adult patients were observed in several children in these studies.
In addition, N-desmethyl metabolite AUC and Cmax values were significantly increased by 200% and 79% respectively.
Co-administration of efavirenz with atorvastatin, pravastatin, or simvastatin did not affect efavirenz AUC or Cmax values.
Clarithromycin AUC and Cmax values were approximately 40% higher than those seen with clarithromycin alone.
A 1 hour infusion schedule wasselected to attain maximum plasma levels(Cmax values) in the range of those observed in the clinic.
Clarithromycin AUC and Cmax values were approximately 40% higher than those seen with clarithromycin alone.
After a single subcutaneous dose of 0.5 mg meloxicam/kg, Cmax values of 2.1 μg/ml were reached after 7.7 hours in young cattle.
Based on Cmax values in rats the systemic exposure in these parenteral studies was approximately 3.5 times higher than the maximum achievable exposure after inhalation.
In addition, in twice daily application, 14 out of 18(78%) and 11 out of 18(61%)reached Cmin values of 1-3 µg/ml and Cmax values of 3-4 µg/ml, whereas in TID application only 4 out of 18(22%) and 7 out of 18(39%) reached these values. .
The dose adjusted Cmax values for the depot formulation were approximately 5% of Cmax from IM standard formulation.
Continuous infusion via the intraperitoneal and intravenous routes(combined data)resulted in higher plasma free insulin Cmax values than multiple daily subcutaneous injections and continuous subcutaneous insulin infusion via an external pump(combined data) in patients with type 1 diabetes mellitus.
Plasma ara-G Cmax values generally occurred at the end of the nelarabine infusion and were generally higher than nelarabine Cmax values, suggesting rapid and extensive conversion of nelarabine to ara-G.
Similarly, mean free and total cobalamins-(III) Cmax values of 197 and 995 µg eq/ ml, respectively, were determined following the dose of 10 g Cyanokit.
Mean free and total cobalamins-(III) Cmax values of 113 and 579 µg eq/ ml, respectively, were determined following a dose of 5 g Cyanokit(the recommended initial dose).
Compared to the subjects with normal renal function, paritaprevir Cmax values were comparable, but AUC values were 19%, 33% and 45% higher in mild, moderate and severe renal impairment, respectively.
Following single intramuscular doses of 0.4 mg meloxicam/kg, a Cmax value of 1.1 to 1.5 μg/ml was reached within 1 hour in pigs.
At the end of weekly dosing for the recommended schedule and dose of 16 mg/kg, the mean(SD)serum Cmax value was 915(410.3) micrograms/mL, approximately 2.9-fold higher than following the first infusion.
The steady-state Cmax value of ceritinib at the recommended clinical dose of 750 mg daily may exceed the Ki values for CYP3A and CYP2C9, suggesting that ceritinib could inhibit the clearance of other medicinal products metabolised by these enzymes at clinically relevant concentrations.
From the population PK model, after the Cycle 6 Day 1 infusion in CLL patients,the estimated median Cmax value was 465.7 μg/mL and AUC(τ) value was 8961 μg•d/mL and in iNHL patients the estimated median Cmax value was 539.3 μg/mL and AUC(τ)value was 10956 μg•day/mL.