Examples of using Cmax values in English and their translations into Hungarian
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AUC and Cmax values were higher in fed than fasted cats.
In younger p atients aged 2-5 years absorption, based on Cmax values, was higher compared to adults.
Cmax values obtained at the end of infusion were higher for BPD-MAD than for BPD-MAC.
The corresponding plasma Cmax values were 24 ng/ml and 47 ng/ml.
Higher Cmax values than in adult patients were observed in several children in these studies.
In addition, N-desmethyl metabolite AUC and Cmax values were significantly increased 79% and 200% respectively.
Mean Cmax values for TMZ and MTIC were 7.4 µg/ml and 320 ng/ml, respectively, following 90 minute intravenous infusion.
Co-administration of efavirenz with atorvastatin, pravastatin,or simvastatin did not affect efavirenz AUC or Cmax values.
Clarithromycin AUC and Cmax values were approximately 40% higher than those seen with clarithromycin alone.
A 1 hour infusion schedule wasselected to attain maximum plasma levels(Cmax values) in the range of those observed in the clinic.
Irbesartan AUC and Cmax values were also somewhat greater in elderly subjects(≥ 65 years) than those of young subjects(18-40 years).
Atazanavir demonstrates nonlinearpharmacokinetics with greater than dose-proportional increases in AUC and Cmax values over the dose range of 200 mg to 800 mg once daily.
However, Cmax values were approximately 30% lower and Cmin values were approximately 28% higher with fosamprenavir.
Similar AUC values for fed vs. fasted and somewhat lower Cmax values(23% for raltegravir and 21% for lamivudine) were observed with DUTREBIS.
AUC and Cmax values of valsartan increase linearly and are almost proportional with increasing dose over the clinical dosing range(40 to 160 mg twice a day).
A selective inhibitor of CYP3A4, ketoconazole(200 mg daily), increased tadalafil(10 mg) exposure(AUC) 2-fold and Cmax by 15%,relative to the AUC and Cmax values for tadalafil alone.
Similarly, mean free and total cobalamins-(III) Cmax values of 197 and 995 µg eq/ ml, respectively, were determined following the dose of 10 g Cyanokit.
AUC and Cmax values were higher in fed than fasted dogs and increased approximately linearly with increasing dose-rates over the intended therapeutic dose range.
In separate single dose studies, at the recommended doses,paediatric patients had comparable AUC and Cmax values of desloratadine to those in adults who received a 5 mg dose of desloratadine syrup.
Based on Cmax values in rats the systemic exposure in these parenteral studies was approximately 3.5 times higher than the maximum achievable exposure after inhalation.
Continuous infusion via the intraperitoneal and intravenous routes(combined data)resulted in higher plasma free insulin Cmax values than multiple daily subcutaneous injections and continuous subcutaneous insulin infusion via an external pump(combined data) in patients with type 1 diabetes mellitus.
AUC and Cmax values were higher in fed than fasted dogs and increased approximately linearly with increasing dose-rates over the intended therapeutic dose range.
Compared to the subjects with normal renal function, paritaprevir Cmax values were comparable, but AUC values were 19%, 33% and 45% higher in mild, moderate and severe renal impairment, respectively.
Plasma ara-G Cmax values generally occurred at the end of the nelarabine infusion and were generally higher than nelarabine Cmax values, suggesting rapid and extensive conversion of nelarabine to ara-G.
Based on in vitro IC50 and in vivo plasma Cmax values, pazopanib metabolites GSK1268992 and GSK1268997 may contribute to the net inhibitory effect of pazopanib towards BCRP.
Mean free and total cobalamins-(III) Cmax values of 113 and 579 µg eq/ ml, respectively, were determined following a dose of 5 g Cyanokit(the recommended initial dose).
In one clinical study, plasma bexarotene AUC and Cmax values were substantially higher following the administration of a fat-containing meal versus those following the administration of a glucose solution.
In addition, N-desmethyl metabolite AUC and Cmax values significantly increased by 200% and 79%, respectively in subjects with severe renal impairment compared to subjects with normal renal function.
In addition, in studies containing only spinosad, AUC and Cmax values were higher in fed than fasted dogs and therefore it is recommended to treat dogs with food as this maximises the opportunity for fleas to ingest lethal amounts of spinosad.