Examples of using Toxicity testing in English and their translations into Slovak
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Assessment of the relevance of long-term toxicity testing on fish.
Chronic toxicity testing shall be conducted in at least one species.
Acute and sub-acute toxicity testing methods.
Long-term toxicity testing on fish,(unless already provided as part of Tier I requirements).
The applicant may consider long-term toxicity testing instead of short-term.
Short-term toxicity testing on invertebrates(preferred species Daphnia).
The registrant may consider long-term toxicity testing instead of shortterm.
In animals, acute toxicity testing is of no relevance as higher doses result in overloading.
Immunoglobulins are normal constituents of the human body, therefore toxicity testing in heterologous species is of no relevance.
Long-term toxicity testing on plants, unless already provided as part of Annex IX requirements.||.
Nanomaterials are one example, as they may possessunique properties which may require new toxicity testing methods and risk prediction tools from the product development phase onwards, to properly consider safety aspects.
Long-term toxicity testing on invertebrates(preferred species Daphnia),(unless already provided as part of Tier I requirements).
Guidance on the design of repeat dose(90-day) studies is provided in VICH GL31: Studies to evaluate the safetyof residues of veterinary drugs in human food: repeat-dose(90 days) toxicity testing(9) and shall be followed.
Results from long-term or reproductive toxicity testing with birds as set out in Section 9.6.1 of Annex X;
Long-term toxicity testing shall be proposed by the applicant if the assessment performed under Tier I indicates the need to investigate further the effects on aquatic organisms.
According to the 2010FTP rules ofAnnex 1 second part2--The smoke and toxicity testing procedures under the condition of high temperature and smoke density detection materials smoke toxicity. .
Long-term toxicity testing shall be proposed by the registrant if the chemicals safety assessment according to Annex I indicates the need to investigate further the effects on aquatic organisms.
When asked at the hearing what specific changes the legislator should make to the PPP Regulation in order to address its alleged failure to assess the cocktail effect, counsel for the defendants suggested imposing an additionalrequirement that industry applicants produce long-term toxicity testing data when seeking an authorisation of their plant protection products.
Reproductive toxicity testing showed no evidence of effects on fertility, embryofetal, or postnatal development.
As regards the possible use of nanomaterials for food use, the Authority considered in its opinion of 6 April 2011 on Guidance on the risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain that limited information is available in relation to aspects of nanotoxicokinetics and toxicology of engineered nanomaterials andthat existing toxicity testing methods may need methodological modifications.
Short-term toxicity testing on fish: The applicant may consider long-termtoxicity testing instead of short-term.
The legal requirements on data relating to human health toxicity testing do indeed differ depending on whether it is an active substance(60) or a plant protection product for which an application is being submitted.
Long-term toxicity testing shall be proposed by the registrant if the results of the chemical safety assessment indicates the need to investigate further the effects of the substance and/or relevant degradation products on sediment organisms.
This Testing Method describes toxicity testing using Lemna gibba and Lemna minor, both of which have been extensively studied and are the subject of the standards referred to above.
Long-term toxicity testing shall be proposed by the registrant if the results of the chemical safety assessment according to Annex I indicates the need to investigate further the effects of the substance and/or degradation products on terrestrial organisms.
The JRC, meanwhile,is focusing on the development and harmonization of methods for the characterization and toxicity testing of manufactured nanomaterials(e.g. particle size measurements, in vitro testing of a representative set of nanomaterials on critical cell lines); related studies on reference materials and dosimetry; studies on the applicability of computational methods for assessing nanoparticle properties, including toxicity; and database development.
Repeated dose toxicity testing and embryo-foetal toxicity studies are impracticable due to induction of, and interference with antibodies.