Examples of using Ipscs in English and their translations into Chinese
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Unfortunately, these iPSCs also have the potential to become cancer.
They applied their technique to produce human neurons by using iPSCs.
The iPSCs cells then generated fully active, cancer-specific T lymphocytes.
But the Japanese teamsaid theirs was the first study to use iPSCs to fix heart damage.
These hypoimmunogenic iPSCs retain their pluripotent stem cell potential and differentiation capacity.
The procedure is themost recent attempt by clinicians to test whether iPSCs can treat disease.
The researchers then expanded these iPSCs and later coaxed them to redifferentiate back into T cells.
The iPSCs were evaluated for genetic stability, rate of pluripotency and several other scientific criteria.
The final step for the researchers was to then guide the iPSCs to become fibroblasts again using other reprogramming factors.
We don't make iPSCs in an organism, we make them in a petri dish in the absence of immune surveillance.
This is one of the firststudies to detail the use of CRISPR in human iPSCs, showcasing its potential in these cells.".
These hypoimmunogenic iPSCs retain their pluripotent stem cell potential and differentiation capacity.
With the right cocktail of molecules and growth factors,the researchers specifically coaxed iPSCs into becoming retinal cells.
When iPSCs were discovered in 2007, there was a lot of hype that we could easily turn them into therapies.
Compared with non-human primate cells, human iPSCs expressed higher levels of these restrictors, called APOBEC3B and PIWIL2.
The iPSCs extracted from traditional cells are highly purified and provide the best stem cells for the isolation of various functional cells.
His lab was also the first to generate patient-specific iPSCs and use them to produce the cell type that degenerated in that individual.
Gan uses iPSCs to produce brain cells, such as neurons or glial cells, because they are relevant to neurodegenerative disease.
But scientists quickly discovered that the DNA-cutting machinery of the CRISPR system, an enzyme known as Cas9,didn't mix well with iPSCs.
Like embryonic stem calls, iPSCs are capable of dividing indefinitely and becoming any cell type present in our body.
The team will develop a way to obtain stage-and subtype-specific heart muscle cells from human iPSCs, which facilitates disease modeling and drug discovery.
These induced pluripotent stem cells(iPSCs) were named the Breakthrough of the Year by the journal Science back in 2008.
For Gabriella, iPSCs are a shoot she can nudge in whatever direction she likes, nurturing and shaping to create any type of cell.
Building on this work, Ding and others previously created iPSCs not with transcription factors, but by adding a cocktail of chemicals to the cells.
We discuss how iPSCs are being exploited to illuminate disease pathophysiology, identify novel drug targets, and enhance the probability of clinical success of new drugs.
Although both CRISPR-Cas9 and human iPSCs have become commonplace in the lab, it's not necessarily easy to unite the two.
Like all stem cells, iPSCs can both self-renew, making more iPSCs, and differentiate into a specialized cell type.
Now scientists regularly use iPSCs to model diseases using cells that would be otherwise difficult to obtain from a living person or animal.
Now scientists regularly use iPSCs to model diseases using cells that would be otherwise difficult to obtain from a living person or animal.
Neural differentiation: iPSCs were differentiated into neurons, expressing βIII-tubulin, tyrosine hydroxylase, AADC, DAT, ChAT, LMX1B, and MAP2.