Examples of using Exons in English and their translations into German
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Colloquial
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Official
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Ecclesiastic
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Medicine
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Financial
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Ecclesiastic
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Political
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Computer
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Programming
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Official/political
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Political
A gene is composed of exons(E) and introns I.
These have all been produced from different combinations of fibronectin gene exons. Sources.
Moreover, younger genes have fewer exons and fewer protein domains.
Exons are nucleotide sequences in DNA and RNA that are conserved in the creation of mature RNA.
Especially mutations in exons 18-20 seems to contribute to protein dysfunction.
Many diseases are caused by the deletion or duplication of exons or whole genes.
It includes 5 exons of which exons 2-5 are coding.
Some of the proteins or parts of the protein may be composed far away from the exons or even located on different chromosomes.
CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44(H-CAM) molecule.
RNA splicing is the method by which pre-mRNA is made into mature mRNA,by removal of introns and joining together of exons.
In many genes, information for proteins encoded by exons is interrupted by regions called introns.
The genes that encode for protocadherin-Î2 andprotocadherin-Î3 also contain three constant regions that are present downstream to the exons.
The method can be used to delete a gene,remove exons, add a gene, and introduce point mutations.
We evaluate and interpret single nucleotide variants(SNVs), small insertions and deletions(INDELs) and copy number variants(CNVs)of single and/or multiple exons.
Mutations of RAS genes at certain hot-spots on exons 2, 3 and 4 result in constitutive activation of RAS proteins independently of EGFR signalling.
Walter Gilbert first put this idea forward,and he proposed that the different permutations of exons could produce different protein isoforms.
A variety of molecular genetic tests are available to diagnose NARP, including mutation scanning of exons, targeted variant analysis, sequence analysis of the entire coding region, sequence analysis of selected exons, and deletion or duplication analysis.
RET mutation status should be assessed according to pre-defined mutational analysis,where type of test and exons to be analyzed are protocol pre-specified.
In addition, as it was previously believed, control regions of a gene neednot remain close to the coding region or exons and introns or somewhere upstream over the DNA or even on the same chromosome.
Introns are removed by RNA splicing as RNA matures, meaning that they are not expressed in the final messenger RNA(mRNA)product, while exons go on to be covalently bonded to one another in order to create mature mRNA.
In Study 58, RET mutation testing was performed by using the polymerase chain reaction(PCR) based Amplification Refractory Mutation System(ARMS) assay for the M918T mutation,and direct sequencing of DNA for mutations in exons 10, 11, 13, 14, 15 and 16(site of M918T mutation) on all sporadic patients where DNA was available 297/298.
Corresponds to exon 3 in humans and mice.
Often one exon contains the recipe for one module within a protein.
Exon 21 L858R gefitinib, in terms of response rate and progression-free survival, is significantly superior as compar- ed to first-line chemotherapy B.
Exon 1 exists in two different splice variants; both regulated by an other promoter.
The mouse exon 3 is an orthologous gene of canine exon 4 that has mutated in case of rcd2 disease.
T in exon 16 of gene that codes for integrin subunit alpha a10β1.
The positioning of the 5' splice site in exon 1 is further supported by interactions between the U5 snRNA and the 3' end of exon 1.
Cleavage of presenilin 1 canbe prevented by a mutation that causes the loss of exon 9, and results in loss of function.
Mutation that causes vWD II is inherited as an autosomal recessive trait,which is associated with a mutation in exon 28 of vWD gene.