Examples of using Systemic absorption in English and their translations into Vietnamese
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Systemic absorption no more than 5%.
With local use, systemic absorption is low.
Systemic absorption after topical application is 12-14%.
When applied topically, systemic absorption is low.
Systemic absorption after topical application of the drug is 12-14%.
Occlusive dressings increase systemic absorption of the drug;
Systemic absorption of ingredients when using the drug does not occur.
Scientists attribute this perceived safety to the low systemic absorption of the medication.
Given the low systemic absorption of the drug, overdose is unlikely.
It is sometimes used in combination with epinephrine to prevent systemic absorption and extend the duration of action.
Systemic absorption of the substance when injected into the bladder is estimated to be very low.
Violations of the vestibular andcochlear systems(if there is a probability of increasing systemic absorption of the drug).
Zucapsaicin displays low systemic absorption and localizes at the area of application.
The greater frequency of decreased hepatic orrenal function in the elderly may delay elimination if systemic absorption occurs.
If signs of overdose or systemic absorption appear, treatment should be stopped immediately.
However, if the dosage is more than 20g of a classI steroid(clobetasol or betamethasone, etc.) some steroid systemic absorption occurs.
Ophthalmic(tobramycin only, Tobrex, or combined with dexamethasone, sold as TobraDex)and nebulised formulations both have low systemic absorption.
Low systemic absorption of indomethacin ointment for external use makes it almost impossible to overdose the drug.
Manifestations of Cushing's syndromealso can be produced in some patients by systemic absorption of topical corticosteroids while on treatment.
Due to the low systemic absorption of human recombinant interferon alfa-2b with its local application, overdose is almost impossible.
This is explained by the fact that Bifosin is intended exclusively for external use, therefore,when properly applied, systemic absorption is extremely low, therefore, the probability of developing overdose symptoms is almost zero.
Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers”. J Clin Pharmacol. 35(11): 1103- 8.
Systemic absorption and adrenal suppression is only a concern if large amounts of potent topical steroids(e.g. more than 100g/week) are used over a long period of time(months).
It should be borne in mind that brinzolamide- the active substance of Azopt- is a sulfonamide,when applied topically, its systemic absorption occurs, and therefore serious adverse reactions may develop, including fatal ones: agranulocytosis, toxic epidermal necrolysis, malignant exudative erythema, hepatonecrosis, aplastic anemia and other disorders of blood formation.
General: Systemic absorption of topical corticosteroids can produce reversible HPA axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal of treatment.
Clinical studies have shown systemic absorption of clindamycin through topical application, in some cases leading to diarrhea, bloody diarrhea, and colitis.
The use of Baneocin, in the presence of systemic absorption, together with antibacterial preparations of the aminoglycoside group and cephalosporins, can increase the risk of developing neurotoxic reactions.