Examples of using Systemic absorption in English and their translations into Polish
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Results demonstrated no systemic absorption.
Systemic absorption is minimal and no interactions are anticipated.
May provide improvement of ocular manifestations,possibly secondary to systemic absorption of the drug.
To reduce the systemic absorption, see section 4.2.
When using nasolacrimal occlusion orclosing the eyelids for 2 minutes, the systemic absorption is reduced.
Systemic absorption occurs mainly through the lungs and is initially rapid then prolonged.
Drug"Viferon"(manual contains the information)has low systemic absorption in the local and external use.
Systemic absorption of CERTIFECT is low for all three active substances following topical administration.
When using nasolacrimal occlusion orclosing the eyelids for 2 minutes, the systemic absorption is reduced.
It is possible that the systemic absorption from 27 mg chewable tablets may be higher than that from 60 mg hard capsules.
In 4 patients, having received a dose of 5, 9, 12 and 17 g, respectively,there were indications of markedly higher systemic absorption.
Systemic absorption of a single dose and multiple applications for 5 consecutive days of becaplermin to those wounds was insignificant.
Systemic absorption of the individual components was minimal and not affected by co-administration in a single formulation.
It is not known whether topical administration to humans could result in sufficient systemic absorption to produce detectable quantities in human breast milk.
This may reduce the systemic absorption of medicinal products administered via the ocular route and result in a decrease in systemic adverse reactions.
It is not known whether topical administration to humans could result in sufficient systemic absorption to produce detectable quantities in breast milk.
Minimal systemic absorption of imiquimod 5% cream across the skin of 58 patients with actinic keratosis was observed with 3 times per week dosing for 16 weeks.
Dinotefuran and pyriproxyfen are partially absorbed by the cat skin(30% and12% respectively), but this systemic absorption is not relevant for the clinical efficacy of the product.
As systemic absorption is largely through the lungs, the use of a spacer plus metered dose inhaler may increase drug delivery to the lungs.
In two 12-month studies of GANFORT(multi-dose formulation) in which systemic absorption was measured, no accumulation was observed of either of the individual components.
Systemic absorption of all active substances was determined in multiple-dose studies after placing the veterinary medicinal product into both ear canals of healthy mixed breed dogs.
The use of Protopy ointment in patients with genetic epidermal barrier defects such as Netherton's syndrome is not recommended due to the potential for permanently increased systemic absorption of tacrolimus.
However, systemic absorption of topically applied olopatadine is minimal with plasma concentrations ranging from below the assay quantitation limit(< 0.5 ng/ml) up to 1.3 ng/ml.
None of the post-dose levels were increased in comparison to the naturally occuring pre-dose levels,showing absence of a relevant systemic absorption after topical administration.
These results for Cmax andAUClast indicate that systemic absorption may depend both on the applied NexoBrid dose(proportional to the covered wound area) and other, patient-specific factors.
Clinical studies have not been performed in patients with impaired renal function, however due to its method of administration andvery low systemic absorption, no dosage adjustment is required.
Systemic absorption of fentanyl increased as a function of time independent of frequency of dosing, with the initial dose being approximately 40% of the nominal 40 micrograms dose absorbed between 12 and 24 hours after application.
During a pharmacokinetic study with Imiquimod 3.75% cream following application of 2 sachets once daily(18.75 mg imiquimod/day) for up to three weeks to the entire faceand/or scalp(approximately 200 cm2), low systemic absorption of imiquimod was observed in patients with AK.
Systemic absorption of the active ingredients was determined in single-dose studies with[14C]- orbifloxacin,[3H]-mometasone furoate and[14C]-posaconazole contained within the Posatex formulation and placed into the ear canals of normal Beagle dogs.