Examples of using Tolerability in English and their translations into Vietnamese
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Safety and tolerability.
With good tolerability of Agapurin, the dose can be doubled, with a maximum of 300 mg.
The specific dose depends on the effectiveness of treatment and tolerability of maprotiline.
In case of good tolerability, increase the dose to 2 ml, starting with the fourth injection.
If the effect is insufficient,the daily dose may then be increased gradually as tolerability permits, but should not exceed 5 mg/kg.
People also translate
Subjective effects and tolerability of the South American psychoactive beverage Ayahuasca in healthy volunteers.".
Deutetrabenazine 24 mg/day and 36 mg/day provided a significant reduction in tardive dyskinesia,with favourable safety and tolerability.
After 4 weeks, depending on the effectiveness and tolerability of the drug, it is increased by 0.1-1 mg/ kg/ day.
With good tolerability of the drug, if necessary, the daily dose is increased to a maximum of 3 g. After improvement, the dose is usually reduced by 3 times.
Child-pugh B: As Vardenafil's clearance to reduce, advice start from 10mg,then according to the tolerability and efficacy gradually increased to 10 mg.
(Cephalalgia 2002; 22, 453-461) Tolerability and efficacy of almotriptan in the long-term treatment of migraine, J. Pascual et al.
These findings suggest that dosing regimens could be individualized andtailored for patients on the basis of dyskinesia control and tolerability.[3].
The clinical and metabolic tolerability of CMA has been demonstrated in numerous clinical studies with duration of treatment of up to 2.5 years.
Treatment begins with a dose of 100 mg 3 times/ day with a gradual increase in the daily dose depending on the clinical course of the disease,the effectiveness and tolerability of the drug.
If the increase in the dose of bisoprololis accompanied by not very good tolerability or a marked decrease in blood pressure, then the increase is carried out once a month.
Depending on the tolerability of the drug and the clinical response, the daily dose can be gradually increased(1 time in 14 days, 500 mg 2 times a day) up to a maximum of 3000 mg.
The rate of dose titration of quetiapine may need to be slower, and the daily therapeutic dose lower, than that used in younger patients,depending on the clinical response and tolerability of the individual patient.
The tolerability of dexmedetomidine hydrochloride was studied in one study in which healthy adult subjects were administered doses at and above the recommended dose of 0.2 to 0.7 mcg/kg/hr.
However, it should be borne in mind that selegilin may enhance the effect of this drug, therefore, a dose adjustment of Levodopa/ Benserazid-Tevamay be required depending on its efficacy and tolerability.
The company used 675 mg and 1,350 mg twice daily doses of controlledrelease nitazoxanide showed favorable safety and tolerability throughout the course of the study, with mild to moderate adverse events.
Jul-Aug;20(6): 290-8 Efficacy, speed of action and tolerability of almotriptan in the acute treatment of migraine: pooled individual patient data from four randomized, double-blind, placebo-controlled clinical trials.
In the PEARL II study, ulipristal acetate has been found to be at least as efficacious as leuprorelin in reducing excessive uterine bleeding caused by uterine myomas anddemonstrated a safety and tolerability profile statistically superior to leuprorelin.
Intended to determine safety and tolerability, pharmacokinetic and pharmacodynamics properties of the drug versus a placebo by utilization of a single IV dose(ranging from 60 to 250 micrograms/kg) in 84 healthy volunteers.
Beginning in October 2016, this is a Phase III/IIb clinical trial to study the efficacy,safety, and tolerability of a vaccine candidate called ALVAC-HIV(vCP2438)+ Bivalent Subtype C gp120/MF59.
For phase one of the REGAIN trial, which took place throughout 2018, the clinical research team at RNTNEH gave the drug via injections to the ear to 15 patients with mild-to-moderate sensorineural hearing loss,to test the safety and tolerability of the drug.
The efficacy and tolerability of a fixed-dose combination of 4 mg perindopril and 5 mg amlodipine, a calcium channel antagonist, has been confirmed in a prospective, observational multicenter trial of 1,250 hypertensive patients.[7] A preparation of the two drugs is available commercially as Coveram.
In our Phase I/II clinical trial using curcumin in patients with pancreatic cancer who were resistant to gemcitabine, a standard therapeutic agent for pancreatic cancer 25,we evaluated the safety and tolerability of curcumin at 8 g/day in combination with gemcitabine-based chemotherapy.
Fesoterodine has the advantage of allowing moreflexible dosage than other muscarinic antagonists.[5] Its tolerability and side effects are similar to other muscarinic antagonists and as a new drug seems unlikely to make great changes in practices of treatment for overactive bladder.[5].
There are differences between estradiol and other estrogens, such as non-bioidentical estrogens like natural conjugated estrogens and synthetic estrogens like ethinylestradiol and diethylstilbestrol,with implications for pharmacodynamics and pharmacokinetics as well as efficacy, tolerability, and safety.[1].
Ebastine has shown overall safety and tolerability profile with no cognitive/psychomotor impairment[1] and no sedation[6] worse than placebo,[2] and cardiac safety, that is, no QT prolongation.[6] The incidence of most commonly reported adverse events was comparable between the ebastine and placebo groups, which confirms that ebastine has a favourable safety profile.