Примери за използване на Is not a substrate на Английски и техните преводи на Български
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Netupitant is not a substrate for P-gp.
Based on in vitro data,alectinib is not a substrate of P-gp.
Macitentan is not a substrate for Pgp/MDR-1.
Rimonabant displays high in vitro permeability and is not a substrate of P-glycoprotein.
Tezacaftor is not a substrate for OATP1B3.
In vitro studies showed that ivacaftor is not a substrate for OATP1B1 or OATP1B3.
Patisiran is not a substrate of cytochrome P450 enzymes.
In vitro studies have shown that degarelix is not a substrate for the human CYP450 system.
Ixazomib is not a substrate of BCRP, MRP2 or hepatic OATPs.
Lusutrombopag is a substrate of P-gp and BCRP, but is not a substrate of OATP1B1, OATP1B3 or OCT1.
Idebenone is not a substrate for p-gp in vitro.
The major primary metabolite M1 is not a substrate of P-gp, BCRP, or BSEP.
Lenvatinib is not a substrate for OAT1, OAT3, OATP1B1, OATP1B3, OCT1, OCT2, or the BSEP.
Eltrombopag is a substrate for BCRP, but is not a substrate for P-glycoprotein or OATP1B1.
Cannabidiol is not a substrate for or an inhibitor of the brain uptake transporters OATP1A2 and OATP2B1.
Fenofibrate is not a substrate for CYP 3A4.
Niraparib is not a substrate of bile salt export pump(BSEP).
Ulipristal acetate is not a substrate for either OATP1B1 or OATP1B3.
Enzalutamide is not a substrate of the efflux transporters P-gp or BCRP.
Fampridine is not a substrate for P-glycoprotein.
Pitolisant is not a substrate of OATP1B1, OATP1B3.
Palbociclib is not a substrate of OATP1B1 or OATP1B3.
In vitro, ataluren is not a substrate for the p-glycoprotein transporter.
Avatrombopag is not a substrate for OATP1B1, OATP1B3, OCT2, OAT1, and OAT3.
Sitagliptin is not a substrate for OCT2 or OAT1 or PEPT1/2 transporters.
Metabolite NW-1153 is not a substrate for OCT2, or OAT1, but it is substrate for OAT3.
Trametinib is not a substrate of CYP enzymes or of the transporters BCRP, OATP1B1, OATP1B3, OATP2B1, OCT1, MRP2, and MATE1.
Caspofungin is not a substrate for P-glycoprotein and is a poor substrate for cytochrome P450 enzymes.
Bedaquiline was not a substrate of MRP2 and BCRP in vitro.
In vitro studies indicated that loxapine was not a substrate for P-glycoprotein(P-gp), but does inhibit P-gp.