Примери за използване на Trough levels на Английски и техните преводи на Български
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The trough levels should be maintained above 5g/l.
Between weeks 9 and 49,median trough levels varied by less than 9%.
Trough levels should be measured in order to adjust the dose and dosage interval.
For most Gram-positive infections, teicoplanin trough levels of at least 10 mg/L when measured by.
Trough levels should be measured and assessed in conjunction with the incidence of infection.
Adjust dosage regimen to clinical response and trough levels of Factor X of at least 5 IU/dL.
Trough levels should be measured and assessed in conjunction with the patient's clinical response.
A strong correlation exists between AUC and whole blood trough levels at steady-state for Envarsus.
The trough levels achieved with the weekly 40 IU/kg dosing regimen are summarised in section 5.2.
A strong correlation exists between AUC and whole blood trough levels at steady-state for Advagraf.
To reduce the rate of bacterial infection, it may be necessary to increase the dose andaim for higher trough levels.
Monitoring of whole blood trough levels therefore provides a good estimate of systemic exposure.
In hepatically impaired patients, it is recommended that sirolimus whole blood trough levels be closely monitored.
In major bleeding episodes, maintain trough levels of VWF: RCo greater than 50% for as long as deemed necessary.
There is no evidence that male andfemale patients require different doses to achieve similar trough levels.
During the dose-adjustment phase, two trough levels were< 5 IU/dL but thereafter none were below this threshold.
Trough levels of 5-10% have been targeted in clinical trials for achieving bleeding control while on prophylaxis.
The Rapamune dose should then be individualised to obtain whole blood trough levels of 4 to 12 ng/mL(chromatographic assay).
Sustained IgG trough levels with a mean concentration of 12.53 g/l were thereby achieved throughout the treatment period.
In comparison to Caucasians,black patients may require higher tacrolimus doses to achieve similar trough levels.
Factor IX trough levels= factor IX activity measured prior to next weekly dose(5 to 10 days post dosing) at steady state.
After repeated dosing in healthy volunteers moxifloxacin increased Cmax of digoxin approximately 30% without affecting AUC or trough levels.
By Day 4, systemic exposure as measured by trough levels is similar for both kidney and liver transplant patients with both formulations.
The pharmacokinetic guided dosing regimen(according to a specific formula) was targeted to maintain factor VIII trough levels≥ 1% at the inter-dosing interval of 72 hours.
The relationship between tacrolimus trough levels(C24) and systemic exposure(AUC0-24) for Envarsus is similar to that of immediate- release tacrolimus.
In subjects with multiple myeloma who received 120 mg every 4 weeks,median trough levels varied by less than 8% between months 6 and 12.
Blood trough levels should be monitored at least twice weekly during the early post-transplant period and then periodically during maintenance therapy.
For endocarditis andother severe infections, teicoplanin trough levels of 15-30 mg/L when measured by HPLC, or 30-40 mg/L when measured by FPIA method.
Dose reduction may be necessary in patients withsevere liver impairment in order to maintain the tacrolimus blood trough levels within the recommended target range.
In the PATH study, subjects(n= 172)achieved sustained trough levels over a period of 24 weeks when receiving weekly doses of 0.2 g/kg bw and 0.4 g/kg bw, respectively.