Examples of using Noncoding in English and their translations into Chinese
{-}
-
Political
-
Ecclesiastic
-
Programming
The other 99 percent is noncoding.
Long noncoding RNAs and human disease.
What is the role of noncoding DNA?
The inclusion of the noncoding genome in our analysis is a leap in the right direction to achieve our goal.".
What are some functions of noncoding DNA?
What's more, most of that noncoding DNA was junk- that is, pieces of DNA that do nothing for us.
In 2006,[biologist David Begun] found some of the first evidence thatgenes could indeed pop into existence from noncoding DNA.
NONCODE is a database of noncoding RNAs(except tRNAs and rRNAs).
The researchers were able to trace theseries of mutations that converted the silent piece of noncoding DNA into an active gene.
A large portion of this so-called noncoding DNA controls the expression of genes, switching them on and off.
What the researchers observed is that some structuralvariants appear to affect regulatory gene“switches” in noncoding sequences of DNA.
We are exploring the noncoding regions to try to discover new parts of the genome that might control different diseases.”.
They also discovered that a new gene mutation in noncoding DNA may have caused gastric cancer.
Circular RNAs, like other noncoding RNAs, were thought to be nonfunctional, but recent evidence suggests otherwise.
What the researchers were able to observe is that some structuralvariants appear to affect regulatory gene"switches" in noncoding sequences of DNA.
This is the first clear demonstration of non-inherited, noncoding mutations causing any complex human disease or disorder.”.
For example, noncoding DNA contains sequences that act as regulatory elements, determining when and where genes are turned on and off.
Gregory likens the search for useful pieces of noncoding DNA to using a metal detector to find gold buried at the beach.
Novartis and Biogen have programs too, andMerck has moved beyond bacterial RNA to investigate the potential for targeting noncoding RNAs.
Position or location of a gene or a DNA marker in a noncoding region is commonly referred to as a locus(plural: loci).
It also validates the notion that transcription of genes can be modulated via smallmolecule compounds engineered to bind to relevant noncoding RNA.
This region of repeated nucleotide called the telomere contains noncoding DNA and hinders the loss of important DNA from chromosome ends.
These noncoding regions have repeatedly been identified by human genetics and cancer genomic studies as potential drivers for human diseases such as cancer.
We will describe the DNA(de)methylation machinery and its association with otherepigenetic mechanisms such as histone modifications and noncoding RNAs.
Scientists have long understood that these noncoding regions play an important role in cancer, but describing that role has been formidably difficult.
Many types of epigenetic processes have been identified- they include DNA methylation, alteration in the structure of histone proteins andgene regulation by small noncoding microRNAs.
Its goal is to target a kind of noncoding RNA called microRNA, two of which are implicated in triple negative breast cancer and glioblastoma.
Here we performed a systematic search to identify breast-cancer-specific small noncoding RNAs, which we have collectively termed orphan noncoding RNAs(oncRNAs).
In addition to protein-coding genes, they surveyed noncoding DNA sequences, which regulate gene activity, and tried to identify which genes these sequences regulate.