Examples of using Glucuronidation in English and their translations into German
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Medicine
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Political
Ritonavir may induce glucuronidation of.
Phenolic glucuronidation is the major phase II metabolic route.
Effects of other medicinal products on glucuronidation of lamotrigine.
The glucuronidation of the active metabolite is catalysed by UGT1A3 and UGT2B7.
UGT1A3 and UGT2B7 are involved in the glucuronidation of the active metabolite.
Bilirubin comes from the degradation of heme in hemoglobin is eliminated by glucuronidation.
D-glucarate supports detoxification via glucuronidation mechanisms, helping to eliminate toxins from DNA.
Irbesartan is mainly metabolised by CYP2C9 and to a lesser extent by glucuronidation.
Oxidation by CYP3A and glucuronidation by UGT2B7 appear to be the major pathways of cobimetinib metabolism.
Firocoxib is metabolised predominantly by dealkylation and glucuronidation in the liver.
The main metabolic processes are demethylenation and glucuronidation, although precise identification of the enzymes involved has not yet been achieved.
Adjunctive therapy WITH valproate inhibitor of lamotrigine glucuronidation- see section 4.5.
Valproate, which inhibits the glucuronidation of lamotrigine, reduces the metabolism of lamotrigine and increases the mean half-life of lamotrigine nearly two-fold.
Estrogens are removed from the circulation via sulfation, glucuronidation, and methylation.
Minor inquietos of purchase flomax professional are glucuronidation, n-dealkylation, hydrolysis, and respiration with dehydrogenation.
Perampanel is extensively metabolised via primary oxidation and sequential glucuronidation.
Bimatoprost then undergoes oxidation, N-deethylation and glucuronidation to form a diverse variety of metabolites.
Celecoxib is metabolised in the liver by hydroxylation, oxidation and some glucuronidation.
Interaction with indinavir/ ritonavir not studied Ritonavir induces glucuronidation and as a result is expected to decrease the plasma concentrations of atovaquone.
The predominant metabolic pathways ofexcreted radioactivity are hydroxylation with subsequent glucuronidation, or hydrolysis.
Induction As a moderate inducer of CYP2C9 anda mild inducer of CYP3A4 and glucuronidation, aprepitant can decrease plasma concentrations of substrates eliminated by these routes.
Secondary biotransformation pathways involving the primary biotransformation products included glucuronidation and dehydrogenation.
Interaction with indinavir/ ritonavir notstudied Ritonavir induces oxidation by CYP2C9 and glucuronidation and as a result is expected to decrease the plasma concentrations of anticonvulsants.
After the end of treatment, EMEND causes a transient moderate induction of CYP2C9 anda transient mild induction of CYP3A4 and glucuronidation.
Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent induces glucuronidation and as a result is expected to decrease the plasma concentrations of atovaquone.
Monotherapy with lamotrigine OR adjunctive therapy WITHOUT valproate and WITHOUT inducers of lamotrigine glucuronidation see section 4.5.
After the end of treatment with the 3-day CINV regimen, aprepitant causes a transient moderate induction of CYP2C9 anda transient mild induction of CYP3A4 and glucuronidation.
Sorafenib is metabolised primarily in the liverand undergoes oxidative metabolism, mediated by CYP 3A4, as well as glucuronidation mediated by UGT1A9.
Propranolol is metabolized through three primary routes: aromatic hydroxylation(mainly 4- hydroxylation),N-dealkylation followed by further side-chain oxidation, and direct glucuronidation.
In a study in 10 male volunteers, rifampicin increased lamotrigine clearance anddecreased lamotrigine half-life due to induction of the hepatic enzymes responsible for glucuronidation.