Examples of using Viral replication in English and their translations into German
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This means that it primarily inhibits viral replication.
The effect of Jakavi on viral replication in patients with chronic HBV infection is unknown.
Ombitasvir is an inhibitor of HCV NS5A which is essential for viral replication.
Current HBV medicines can effectively suppress viral replication, but achieve a cure in fewer than 3% of patients and do not eliminate the risk of liver cancer.
The virus is then engulfed by the cell,which serves as a factory of sorts for viral replication.
Experience in patients with persistent viral replication study GS-US-174-0106.
Telaprevir is an inhibitor of the HCV NS3•4A serine protease, which is essential for viral replication.
Introduced to the market in 1996, Crixivan stops viral replication by inhibiting the activity of protease, an enzyme used by viruses to cleave nascent proteins for final assembly of new virons.
Simeprevir is a specific inhibitor of the HCV NS3/4A serine protease, which is essential for viral replication.
All clinical trials recruited patients withchronic hepatitis B who had active viral replication measured by HBV DNA, elevated levels of ALT and a liver biopsy consistent with chronic hepatitis.
Another unique feature of the FV Envprotein is its essential role late in the viral replication cycle.
Clinical trial results All clinical trials recruited patients withchronic hepatitis B who had active viral replication measured by HBV DNA, elevated levels of ALT and a liver biopsy consistent with chronic hepatitis.
Raltegravir inhibits the catalytic activity of integrase, an HIV-encoded enzyme that is required for viral replication.
Compensated liver disease and evidence of immune active disease, i.e. active viral replication, persistently elevated serum ALT levels and histological evidence of active inflammation and/or fibrosis see sections 4.4, 4.8 and 5.1.
However, once the disease is present, antiviral drugs can only curb viral replication but not stop it.
In addition, raltegravir inhibited viral replication in cultures of mitogen-activated human peripheral blood mononuclear cells infected with diverse, primary clinical isolates of HIV-1, including isolates resistant to reverse transcriptase inhibitors and protease inhibitors.
Sofosbuvir is a pan-genotypicinhibitor of the HCV NS5B RNA-dependent RNA polymerase, which is essential for viral replication.
As well as shielding the genome,nucleoprotein helps to control the balance between the production of proteins needed for viral replication and the process of replication itself, because both cannot happen simultaneously.
This allows the viral membrane to fuse with the cell membrane andrelease the genetic material used in viral replication.
In addition, raltegravir inhibited viral replication in cultures of mitogen-activated human peripheral blood mononuclear cells infected with diverse, primary clinical isolates of HIV-1, including isolates from 5 non-B subtypes, and isolates resistant to reverse transcriptase inhibitors and protease inhibitors.
The approach aims at inhibitionof the highly conserved host cell proteasome which is essential for viral replication.
Furthermore, the finding that one patient controlled viral replication to below the limit of detection and remained off ART for 22 weeks is very intriguing and is currently under intensive evaluation", said Ole Schmeltz SÃ̧gaard, MD, PhD, Associate Professor at the Aarhus University Hospital and principal investigator of the study, Department of Infectious Diseases, Aarhus, Denmark.
Such as Chinese medicine astragalus extract to join, can stimulate the body produce interferon,interference viral replication, improving the body immunity.
Grazoprevir is an inhibitor of the HCV NS3/4A protease which is necessary for the proteolytic cleavage of the HCV encoded polyprotein(into mature forms of the NS3, NS4A, NS4B, NS5A, and NS5B proteins)and is essential for viral replication.
Clinically significant reduction of susceptibility to abacavir has beendemonstrated in clinical isolates of patients with uncontrolled viral replication, who have been pre-treated with and are resistant to other nucleoside inhibitors.
The research group's aim is to decipher three dimensional enzyme structures in the virus and to develop active agents thattarget these and inhibit viral replication.
Mice deficient in peripheral or CNS-specific IFN response will provide insight into,how type I IFN response regulates viral replication and spread, neuro-invasion and neuro-pathology.
When foamy carbon, poly(N-vinyl-2-pyrrolidone), and bovine serum albumin were tested as capping agents for silver nanoparticles,the foamy carbon appeared to have the greatest inhibitory effect on viral replication.
Deletion of ICP47 prevents down- regulation of antigen presentation molecules and increases the expression of HSV US11 gene,thereby enhancing viral replication in tumour cells.
Paritaprevir is an inhibitor of HCV NS3/4A protease which is necessary for the proteolytic cleavage of the HCV encoded polyprotein(into mature forms of the NS3, NS4A, NS4B, NS5A,and NS5B proteins) and is essential for viral replication.