Examples of using Prograf in English and their translations into Portuguese
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Conversion between Modigraf and Prograf tacrolimus formulations.
Prograf and associated names See Annex I.
Advagraf is taken once daily, while Prograf is taken twice daily.
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However, Advagraf is taken once daily, whereas Prograf is taken twice daily.
Advagraf and Prograf are not interchangeable.
The relationship between tacrolimus trough levels(C24) and systemic exposure(AUC0-24)for Advagraf is similar to that of Prograf.
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This allows Advagraf to be given once a day, whereas Prograf/ Prograft is given twice a day.
Prograf and Advagraf both contain the active substance, tacrolimus.
Clinical efficacy and safety of Prograf capsules bid in primary organ transplantation.
Prograf and associated names(see Annex I) 5 mg/ ml concentrate for solution for infusion.
The second study compared Envarsus with Prograf as part of standard treatment in 543 patients with a newly transplanted kidney.
Prograf and associated names(see Annex I) 0.5 mg hard capsules[See Annex I- To be completed nationally] Tacrolimus.
Treatment emergent fatal adverse events occurred in 1.2% of Envarsus patients and 0.6% of Prograf patients.
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Envarsus has been shown to be at least as effective as Prograf in two main studies in patients with kidney transplants.
Prograf is used to prevent the body from rejecting a heart, liver, or kidney transplant and to treat rheumatoid arthritis.
Failure rates were 2.5% in both groups 4 of 162 patients treated with Envarsus, and4 of 162 treated with Prograf.
The efficacy andsafety of Advagraf and Prograf, both in combination with corticosteroids, was compared in 471 de novo liver transplant recipients.
The relationship between tacrolimus trough levels(C24) and systemic exposure(AUC 0-24)is similar between the two formulations Advagraf and Prograf.
These studies compared Envarsus with Prograf, a widely used and well-established tacrolimus medicine that releases tacrolimus more quickly.
Treatment failure occurred in 18.3% patients treated with Envarsus(49 out of 268), and 19.6% given Prograf 54 out of 275.
The efficacy andsafety of Advagraf and Prograf, both in combination with mycophenolate mofetil(MMF) and corticosteroids, was compared in 667 de novo kidney transplant recipients.
The shorter studies in kidney andliver transplant patients showed that Advagraf and Prograf/ Prograft have comparable absorption in the body.
Similarly, for conversion of patients from Prograf capsules to Modigraf granules, the total daily Modigraf dose should preferably be equal to the total daily Prograf dose.
The dose recommendations for lung, pancreas andintestinal transplantation are based on limited prospective clinical trial data with the Prograf formulation.
The efficacy andsafety of Envarsus and Prograf, both in combination with mycophenolate mofetil(MMF) or mycophenolate sodium(MPS) and corticosteroids, was compared in 324 stable kidney transplant recipients.
The first study involved 326 patients who had already had a kidney transplant andwere being treated with Prograf and other immunosuppressants to prevent rejection.