Examples of using Polymorphisms in English and their translations into Slovak
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Medicine
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Populations and genetic polymorphisms.
Polymorphisms in drug metabolising enzymes.
Subjects with baseline NS5A polymorphisms,*.
Several polymorphisms of CYP2E1 have been identified.
Subjects without baseline NS5A polymorphisms,*.
Multiple polymorphisms of FGF-21 have been identified.
SVR by presence of baseline NS5A resistance-associated polymorphisms†,§.
Genetic polymorphisms of alcohol metabolizing enzymes.
Overall prevalence of GT4-infected subjects with baseline NS3 polymorphisms in the pooled analyses was 19%(7/36).
There are two polymorphisms of MTHFR reducing its activity.
Despite the fact, that there are multiple known lambda chain isotypes,there have not been reported any lambda chain serological polymorphisms.[9].
Patients with genetic polymorphisms affecting CYP3A4 and CYP3A5.
Polymorphisms are naturally occurring single nucleotide variations of a gene present in more than 1% of the population.
They searched for single-nucleotide polymorphisms(SNPs) as well as for rarer copy number variations(CNVs).
NS3 polymorphisms considered were any amino acid substitution at positions 36, 54, 55, 56, 80, 107.
UGT1A1 activity is reduced in individuals with genetic polymorphisms that lead to reduced enzyme activity such as the UGT1A1*28 polymorphism.
MTHFR polymorphisms are estimated to occur in up to 57% of the population.
Data from various strains of full length NS5A replicons or chimeric NS5A replicons carrying full-length NS5A genes thatcontain L31 or M31 polymorphisms.
Single nucleotide polymorphisms(SNPs) in the BTD genome has the following components.
The observed treatment response differences by treatment regimen in specific patient populations in the presence or absenceof baseline NS5A or NS3 polymorphisms are summarised in Table 7.
Do Genes and Polymorphisms Explain the Differences between Eastern and Western Societies?
If we are lucky enough to have their single nucleotide polymorphisms(SNPs), we can really help them decide on the best strategy for pain management.
Genetic polymorphisms are naturally occurring variants in gene structure that occur in more than 1 percent of the population.
Cytochrome P450 2C9 activity is reduced in individuals with genetic polymorphisms that lead to reduced enzyme activity, such as those homozygous for the CYP2C9*3 polymorphism.
Genetic variability(polymorphisms) in these enzymes may influence a patient's response to commonly prescribed drug classes.
Cytochrome P450 CYP2C9 activity is reduced in individuals with genetic polymorphisms that lead to reduced enzyme activity, such as those homozygous for the CYP2C9*3 polymorphism.
There is no evidence that common polymorphisms in drug metabolising enzymes alter dolutegravir pharmacokinetics to a clinically meaningful extent.
Published literature has indicated that the CYP3A4*22 and CYP3A5*3 single nucleotide polymorphisms influence fentanyl to norfentanyl metabolism with the potential for increased fentanyl exposure in patients with these genetic polymorphs.
Liver and kidney function, cytochrome P450 polymorphisms and ageing are not expected to influence the clinical efficacy or safety of Glybera.
CYP2C9 activity is reduced in individuals with genetic polymorphisms that lead to reduced enzyme activity, such as those homozygous for the CYP2C9*2 and CYP2C9*3 polymorphisms.