Приклади вживання Multiple doses Англійська мовою та їх переклад на Українською
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Is it safe to administer multiple doses of OPV to children?
The mean plasma eliminationhalf-life is 21 hours after single or multiple doses.
When using multiple doses( 5-20 mg 1 time per day) pharmacokinetic parameters were not changed.
After arriving to the hospital, he was given multiple doses of Narcan.
The plasma levels obtained after multiple doses are similar to those achieved after a single dose. .
This is the most common preservative used in the vaccines supplied in vials for multiple doses.
If you wish to approach the upper end of the range,you can take multiple doses before your 2-3 biggest meals of the day.
This is the most common preservative used in the vaccines supplied in vials for multiple doses.
Following concomitant administration of asingle dose of leflunomide to subjects receiving multiple doses of rifampicin(non-specific cytochrome P450 inducer) A771726 peak levels were increased by approximately 40%, whereas the AUC was not significantly changed.
Glutamine can be taken either with or without meals and in one single dose or multiple doses.
In uninfected volunteers, multiple doses of 200 to 400 mg per day for 10 days resulted in a lower than predicted extent of accumulation(22 to 42% lower) and a shorter terminal half-life of 40 to 55 hours(single dose half-life 52 to 76 hours).
The answer to this is really no different than this same question about any other vaccine that is given in multiple doses.
After concomitant administration of a singledose of equipoise dosage subjects who received multiple doses of rifampicin(non-specific inducer of cytochrome P450), A771726 peak levels increased by approximately 40%, whereas the area under the concentration-time curve is not significantly changed.
In accordance with the half-life, theaccumulation index is 5 to 6 based on AUC0-24h following multiple doses of 5 to 20 mg/day.
The pharmacokinetics of cephepime was studied in children from2 months to 11 years after a single and multiple doses according to the programs every 8 hours and every 12 hours.
In elderly healthy subjects(aged≥65 years; n=20), the exposure to vortioxetine increased up to 27%(Cmax and AUC)compared to young healthy control subjects(aged≤45 years) after multiple doses of 10 mg/day.
A vaccine is an antigenic preparation used to produce active immunity to a disease, in order to prevent or reduce the effects of infection by any natural or"wild" pathogen.[1]Many vaccines require multiple doses for maximum effectiveness, either to produce sufficient initial immune response or to boost response that fades over time.
The overall exposure of adolescents(12 to≤17 years) and children(2 to<12 years)to deferasirox after single and multiple doses was lower than that in adult patients.
MGL-3196 has completed Phase I single and multiple dose trials in healthy volunteers.
Upon multiple dosing exposure increased by an accumulation factor of 1.3 to 2.3.
Upon multiple dosing, plasma concentrations of bosentan decrease gradually to 50- 65% of those seen after single dose administration.
In multiple dose studies in patients with rheumatoid arthritis, the pharmacokinetic parameters of A771726 were linear over the dose range of 5 to 25 mg.
Multiple dose pharmacokinetic studies demonstrated that the AUC of galantamine increased 30% and 40%, respectively, during coadministration of ketoconazole and paroxetine.
In multiple dose studies in patients with rheumatoid arthritis, the pharmacokinetic parameters of A771726 were linear over the dose range of 5 to 25 mg.
Absorption is almost complete and independent of food intake(mean time tomaximum concentration is 4 hours after multiple dosing).
Gabapentin elimination half-life is 5 to 7 hours andis unaltered by dose or following multiple dosing.
There is a considerable inter-patient variation in plasma levels,both after single and multiple dosing.
A phase 1B randomized multiple dose escalation study reported that administration of 40 mg doses of NSI-189 once/day, 40 mg twice/day, and 40 mg three/day for 28 days.
Following multiple dose administration of NAMENDA 20 mg daily, females had about 45% higher exposure than males, but there was no difference in exposure when body weight was taken into account.