Examples of using Codon in English and their translations into Slovak
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Each codon is three bases.
Specific gene, codon.
Pronounce Codon in English.
P53 gene mutation at codon 55.
Codon pronunciation in English[en].
So three base pairs make a codon.
Anticodon arm- It is attached to the codon of the messenger RNA.
There exists a special tRNA molecule for each codon.
A mutation that occurs as an error in a codon of a DNA or RNA molecule.
A"Stop" codon is a codon that signifies that the end of the protein has been reached- and for obvious reasons is usually found at the end of the base-pair sequence coding for the protein.
Additional mutations in KRAS and NRAS at exon 3(codon 59) were subsequently identified(n= 7).
The O-tRNA anticodon loop recognizes the selector codon on the mRNA and incorporates its amino acid, e.g., an unnatural amino acid, such as an alkynyl amino acid, at this site in the polypeptide.
Most IDH mutations are associated with codon 132 and 172 in IDH1 and IDH2 in gliomas, respectively.
Preclinical data generated in biochemical assays demonstrated thatdabrafenib inhibits BRAF kinases with activating codon 600 mutations(Table 5).
Diane: Is this new codon activation found only in newborn children?
Ataluren enables ribosomalreadthrough of mRNA containing such a premature stop codon, resulting in production of a full-length protein.
Single nucleotide substitution in the normal stop codon is located, on the contrary, can make it meaningful, then the mutant mRNA and then the mutant polypeptide are longer than normal.
Because you have to have three base pairs that code for one amino acid, and actually, three base pairs,this is called a codon, because it codes for amino acids.
It is the same in the case that mutation changes codon in a different one, synonymous- coding the same amino acid.
Preclinical data generated in biochemical assays demonstrated that vemurafenib canpotently inhibit BRAF kinases with activating codon 600 mutations(table 6).
The O-tRNA recognizes the first selector codon, and the O-RS preferentially aminoacylates the O-tRNA with pPRO-Phe.
The NUCLEUS library provides higher-level functions specific to molecular sequence analysis, including sequence comparisons,translation, codon usage and annotation.
(t) Estimated from 16,403 melanomas with annotated BRAF codon 600 mutations in the public COSMIC database, release 71(November 2014).
Abacavir-resistant isolates of HIV-1 have been selected in vitro and in vivo andare associated with specific genotypic changes in the RT codon region(codons M184V, K65R, L74V and Y115F).
These include, for example, pVL985 which alters the polyhedrin start codon from ATG to ATT, and which introduces a BamHI cloning site 32 basepairs downstream from the ATT; see Luckow and Summers, Virology(1989) 17:31.
Abacavir-resistant isolates of HIV-1 have been selected in-vitro in wild-type strain HIV-1(HXB2)and are associated with specific genotypic changes in the RT codon region(codons M184V, K65R, L74V and Y115).
Resistance: HIV-1 resistance to emtricitabine develops as the result of changes at codon 184 causing the methionine to be changed to a valine(an isoleucine intermediate has also been observed) of the HIV reverse transcriptase.
Thus for any given codon position where both natural and novel amino acids can be inserted, other than a probability of incorporation, there is relatively little control over which amino acid will end up being inserted.
The cell further comprises: an orthogonal-tRNA(O-tRNA)that functions in the cell and recognizes the selector codon; and, an orthogonal aminoacyl-tRNA synthetase(O-RS) that preferentially aminoacylates the O-tRNA with the DHP.