Examples of using Interim analysis in English and their translations into Slovenian
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Interim analysis.
Pre-specified interim analysis.
An interim analysis was performed with a median follow up of 55 months.
Survival continued to be followed after the interim analysis.
The interim analysis for OS was conducted when 331 events were observed.
The trial was stopped for futility after an interim analysis.
This interim analysis showed a TTP risk reduction of 45%(95% CI: 29-57%), p< 0.0001.
An objective response was observed for four of six evaluable adolescent in an interim analysis of Study 5.
An interim analysis was performed when all subjects had completed the month 48 study visit.
CI= confidence interval a The Phase 3study ALSYMPCA was stopped for efficacy after the interim analysis.
At an interim analysis of the on-going registry, data from 96 patients with severe VOD were available.
The study was un-blinded after this planned interim analysis of OS had crossed the pre-specified efficacy boundary.
In an interim analysis of the ERADICATE trial, 40 of the 50 patients had reached 12 weeks post treatment and had SVR12 rates of 98 percent(n=39/40).
Central laboratory drug susceptibility testing results became available for oneadditional placebo subject after the week 24 interim analysis.
At the time of the interim analysis 40 patients have reached 12 weeks post treatment and SVR12 was 98%(39/40).
The interim analysis of a recent multicentre study discussed 110 patients who underwent 1:1 randomisation to either tacrolimus or ciclosporin.
Criteria for statistical significance at the interim analysis of OS was a p-value≤ 0.00274(using Lan DeMets spending function approximating O'Brien Fleming boundary).
An interim analysis of RE-VERSE AD included data for 123 patients: 66 patients with serious bleeding(Group A) and 57 requiring an urgent procedure(Group B).
Since data from the trial were included in an interim analysis, a two-sided 95.02% confidence interval applied which corresponds to a p-value of less than 0.0498 for significance.
This interim analysis showed a TTP risk reduction of 45%(95% CI; 29-57%, p< 0.0001) for patients treated with combination therapy of bortezomib and pegylated liposomal doxorubicin.
GA pre-specified interim analysis for OS was performed based on a minimum follow-up time of 35.4 months.
An interim analysis showed there was a significant prolongation of the time to progression of disease in the 10 mg/ kg group as compared with the placebo group(hazard ratio, 2.55; p< 0.001).
The 180/1.3 arm was stopped after an interim analysis, as prespecified in the protocol, when the two active-treatment arms appeared to have a similar incidence of bleeding.
In an interim analysis of an ongoing clinical outcome study, an independent safety monitoring committee identified a higher than expected incidence of myopathy in Chinese patients taking Pelzont and simvastatin 40 mg.
The trial was stopped after an interim analysis due to a low likelihood of demonstrating a significant difference in 28-day mortality by the end of the trial.
Lung transplantation The interim analysis of a recent multicentre study discussed 110 patients who underwent 1:1 randomisation to either tacrolimus or ciclosporin.
Of some relevance is the interim analysis data from the ongoing case-control study of the progestogen releasing contraceptive IUD(Mirena)(ICPE meeting report, 2008).
The protocol pre-specified interim analysis after 520 deaths showed a statistically significant superiority in overall survival in patients treated with enzalutamide compared to placebo(Table 3 and Figures 4 and 5).