Examples of using Isoforms in English and their translations into Arabic
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Colloquial
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Political
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Ecclesiastic
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Ecclesiastic
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Computer
Dutasteride inhibits both isoforms of 5a-reductase, therefore preventing the conversion of into.
Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen(4-OHT)and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4.
So far, eight different isoforms of glutathione peroxidase(GPx1-8) have been identified in humans.
Differential gene expression tools can also be used for differential isoform expression if isoforms are quantified ahead of time with other tools like RSEM.
There are three known isoforms in mammals, two are constitutive(cNOS) and the third is inducible(iNOS).
The relationship between bullous pemphigoid(BP) and neurological disease has been the subject of numerous recent studies andBP antigens and their isoforms have been identified in the central nervous system(CNS).
A novel polyurethane elastomer curing agent, of which there are two isoforms that 2,4- and 2,6- dimethyl sulfur based toluene diamine mixture(about 77~80/17~20), and usually use the MOCA compared to room temperature is low viscosity liquid, can be used in low temperature operation chemically using low equivalent.
Of the three follistatin domains present in all follistatin isoforms, the first two, but not the third, are necessary for activin A binding.
Three isoforms are known for the NOS enzyme: endothelial(eNOS), neuronal(nNOS), and inducible(iNOS)- each with separate functions. The neuronal enzyme(NOS-1) and the endothelial isoform(NOS-3) are calcium-dependent and produce low levels of this gas as a cell signaling molecule. The inducible isoform(NOS-2) is calcium-independent and produces large amounts of gas that can be cytotoxic.
L-arginine + 3/2 NADPH + H+ + 2 O2 formula_1 citrulline +nitric oxide + 3/2 NADP+NOS isoforms catalyze other leak and side reactions, such as superoxide production at the expense of NADPH.
FGFR2 has two naturally occurring isoforms, FGFR2IIIb and FGFR2IIIc, created by splicing of the third immunoglobulin-like domain. FGFR2IIIb is predominantly found in ectoderm derived tissues and endothelial organ lining, i.e. skin and internal organs.[8] FGFR2IIIc is found in mesenchyme, which includes craniofacial bone and for this reason the mutations of this gene and isoform are associated with craniosynostosis.
Various human GALE mutations resulting in TypeIII galactosemia have been identified.[6] Functional analysis of these mutant GALE isoforms suggests that reduced catalytic efficiency and increased likelihood of proteolytic digestion act causatively in Type III galactosemia.
The interaction of follistatin with heparin and heparan sulfates is isoform specific.
Fetal fibronectin(fFN), an isoform of fibronectin, is a complex adhesive glycoprotein with a molecular weight of approximately 500,000 daltons.
Long-read sequencing captures the full transcript andthus minimizes many of issues in estimating isoform abundance, like ambiguous read mapping. For short-read RNA-Seq, there are multiple methods to detect alternative splicing that can be classified into three main groups:[101][102][103].