Examples of using Isoforms in English and their translations into Vietnamese
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There are 2 isoforms of ADA: ADA1 and ADA2.
There are 4 confirmed SUMO isoforms in humans;
There are two isoforms of monoamine oxidase, MAO-A and MAO-B.
Cyclooxygenase(COX) has two well-studied isoforms, called COX-1 and COX-2.
Production of the primary metabolite, ucb L057,is not supported by liver cytochrome P450 isoforms.
Serum levels of 20K-hGH and 22K-hGH isoforms in acromegalic patients.
Alternative splicing of the GNRHR gene, GNRHR,results in multiple transcript variants encoding different isoforms.
These genes have splice variants that encode for several isoforms that are marked by a suffix.
There are two isoforms of ACE: the somatic isoform, which exists as a glycoprotein comprised of a single polypeptide chain of 1277;
Plakophillins have 9-arm repeats, and exist in 2 isoforms: a shorter"a" form and longer"b" form.
Furthermore, there's not a lot of information available about theexcretion of various human growth hormone isoforms in the urine.
The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative….
Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.[1].
The IR may be expressed in two different isoforms, A and B, produced by an alternative splicing of the IR gene transcript(Moller et al. 1989).
The gene is expressed in both male and female flies and is subject to alternative splicing,producing the protein isoforms dsxf in females and the longer dsxm in males.
Brolucizumab binds to the three major isoforms of VEGF-A(e.g., VEGF110, VEGF121, and VEGF165), thereby preventing interaction with receptors VEGFR-1 and VEGFR-2.
Like other members of the anthranilic acid derivatives(or fenamate) class of NSAID drugs,it inhibits both isoforms of COX and prevents formation of prostaglandins.[3][9].
Linker histones such as H1 and its isoforms are involved in chromatin compaction and sit at the base of the nucleosome near the DNA entry and exit binding to the linker region of the DNA.
Much of the specificity within the NF-κB signalling pathway depends on these IκB isoforms being able to bind to different dimers of the NF-κB/Rel family.
Four isoforms of the 4-O GalNAc sulfotransferases(C4ST-1, C4ST-2, C4ST-3, and D4ST-1) and three isoforms of the GalNAc 6-O sulfotransferases(C6ST, C6ST-2, and GalNAc4S-6ST) are responsible for the sulfation of GalNAc.[6].
Of the three follistatin domains present in all follistatin isoforms, the first two, but not the third, are necessary for activin A binding.
Cytochrome P450 enzymes: In vitro studies using human liver microsomes indicate that fenofibrate and fenofibric acid are not inhibitors of cytochrome(CYP)P450 isoforms CYP3A4, CYP2D6, CYP2E1, or CYP1A2.
There are at least 11 known human tropoelastin isoforms. these isoforms are under developmental regulation, however there are minimal differences among tissues at the same developmental stage.
It is unknown what role the relatively bulky extracellular region of CD45 plays during cell interactions,but CD45 has various isoforms that change in size depending on the Th cell's activation and maturation status.
Mature B cells have both immunoglobulin M(IgM) and IgD types of BCRs, which have identical antigen-binding sites and are both associated with the signaling subunits Igα and Igβ,but differ in their membrane-bound heavy chain isoforms.
Ribose-phosphate pyrophosphokinase exists in bacteria, plants, and animals, and there are three isoforms of human ribose-phosphate pyrophosphokinase.[2] In humans, the genes encoding the enzyme are located on the X chromosome.[2].
The results of this study indicate that patients with BP and neurological disease exhibit an immune response to both BP180 and BP230, thus the link between the CNS and the skin is not dependent on a specific antigen,but possibly both antigens or their isoforms may be exposed following a neurological insult, and play a role in generation of an immune response.
Ponatinib was intended to target not only native BCR-ABL,but also its isoforms that carry mutations that confer resistance to treatment with existing tyrosine kinase inhibitors, including especially the T315I mutation for which no effective therapy exists.[15].
The protein belongs to a family of isozymes, including cyclophilins B and C, and natural killer cell cyclophilin-related protein.[2][3][4]Major isoforms have been found within single cells, including inside the Endoplasmic reticulum, and some are even secreted.
The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues.[4]Multiple transcript variants encoding different isoforms have been found for this gene.[4] Elastin's soluble precursor is tropoelastin.[5] The characterization of disorder is consistent with an entropy-driven mechanism of elastic recoil.