Examples of using Sofosbuvir in English and their translations into Chinese
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Sofosbuvir pricing in high-income countries.
One tablet contains 400 mg of Sofosbuvir and 100 mg of Velpathaswir.
Sofosbuvir's price has generated debates about sustainability.
Increasing numbers of Chinesehave been traveling to India to purchase Sofosbuvir.
Sofosbuvir(PSI-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM.
The drug has shown a 100% curerate in as little as 6 weeks in combination with sofosbuvir.
In genotype 2 and 3 HCV infections, sofosbuvir can be used in combination with daclatasvir.
Sofosbuvir(SOF), which is easily available in the developing world, is taken as a 400-mg tablet once daily.
The NS5B nucleoside polymerase inhibitor sofosbuvir has the highest barrier to resistance[82].
Sofosbuvir's registration- approval by each national regulatory authority for each medicine is an inescapable process.
Asked Hany Tawfik, 66, a private equity specialist who in2014 was the first Egyptian to receive sofosbuvir.
Sofosbuvir is in the nucleotide analog family of medication and works by blocking the hepatitis C NS5B protein.
No previous treatments resulted in a sustained virologic response,which made sofosbuvir a highly sought-after drug.
The majority of the sofosbuvir dose recovered in urine was GS-331007(78%) while 3.5% was recovered as sofosbuvir.
In late 2013, two new HCV therapies were approved by the FDA,simeprevir(Olysio) and sofosbuvir(Sovaldi)1.
The majority of the sofosbuvir dose recovered in urine was GS-331007(78%) while 3.5% was recovered as sofosbuvir.
Results of all clinical trials showed that a treatment regimen containing sofosbuvir was effective in treating multiple types of HCV.
Sofosbuvir is a substrate of drug transporter P-gp and breast cancer resistance protein(BCRP) while GS-331007 is not.
Hemodialysis can efficiently remove the predominant circulating metabolite of sofosbuvir, GS-331007, with an extraction ratio of 53%.
Sofosbuvir(Sovaldi) received FDA approval in 2013, and was the first drug deemed safe and effective without interferon.
The ASTRAL-3 trial reported an SVR 12 of95% in genotype 3 patients treated with sofosbuvir+ velpatasvir for 12 weeks[57].
Sofosbuvir is a substrate of drug transporter P-gp and breast cancer resistance protein(BCRP) while GS-331007 is not.
Tell your doctor or dentist that you take Ledipasvir& Sofosbuvir before you receive any medical or dental care, emergency care, or surgery.
Sofosbuvir is a substrate for The p-glycoprotein Transporter drug and the breast cancer resistance protein(BCRP), and GS-331007 is not a substrate.
Other drugs, such as boceprevir, telaprevir and sofosbuvir, have been shown to improve this cure rate, though all carry additional side effects.
One of the most recent FDA-approved pan-genotype combinations, available under the trade name Epclusa,contains sofosbuvir+ velpatasvir[55].
Sofosbuvir, daclatasvir and the sofosbuvir/ledipasvir combination are part of the preferred regimens in the WHO guidelines, and can achieve cure rates above 95%.
We have been able to attain strong market goodwill as a trustedorganization engaged in offering our clients Sovihep Sofosbuvir 400 mg Tablets.
This study systematically compared the price and affordability of sofosbuvir and ledipasvir/sofosbuvir across 30 countries to assess affordability to health systems and patients.
Gilead has entered into licensingdeals with several manufacturers in India to provide generic sofosbuvir to more than 100 low- and middle-income countries.